High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache. Nausea and vomiting. Diarrhea.
Even the lowest doses in B12 supplements are many times the recommended dietary allowance. Doses up to 1,000 mcg, though unnecessary, aren't harmful.
Excess B12 is either stored in the liver, present in the blood without any adverse effects, or excreted. There are no studies investigating the potential clinical effects of high B12 because, in general, there are no known adverse effects caused by elevated B12.
If you take vitamin B12 supplements, do not take too much as this could be harmful. Taking 2mg or less a day of vitamin B12 in supplements is unlikely to cause any harm.
It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. If you have hydroxocobalamin injections to boost your vitamin B12 levels at the start of treatment, the cyanocobalamin tablets may start to work within a few days.
Generally 120-680 pmol/L.
Vitamin B12 is considered an important brain and nervous system micronutrient and is often used for anxiety. It helps to ensure normal function for your nerves, which can help combat physical symptoms of anxiety.
Stage 1 is decreased levels of vitamin B12 in the blood. Stage 2 is low concentration of vitamin B12 in the cell and metabolic abnormalities. Stage 3 is increased levels of homocysteine and MMA and decreased DNA synthesis resulting in neuropsychiatric symptoms. Stage 4 is macrocytic anemia.
While B12 doesn't directly provide energy, it does give the body the tools it needs to convert food molecules into energy. Getting the recommended daily amount of B12 can therefore help ensure that the body is able to make the energy it needs to do everything you need it to do.
Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment. If you can, it's a good idea to address what's causing the deficiency.
B12 injections may contribute to low potassium levels in your body. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat.
Nervous System Reactions
After getting a vitamin B12 injection some people may experience a disturbance to the nervous system. These symptoms may include dizziness, difficulty walking normally, nervousness, anxiety, weakness and uncoordinated movements.
Vitamin B12 deficiency can have distressing neuropsychiatric symptoms. It can have an etiological role in clinical presentations like depression, anxiety, psychosis, dementia, and delirium, requiring screening of at-risk populations.
Weakness, tiredness, or lightheadedness. Heart palpitations and shortness of breath. Pale skin. A smooth tongue.
Symptoms of vitamin B12 or folate deficiency
extreme tiredness. a lack of energy. pins and needles (paraesthesia) a sore and red tongue.
feeling weak or tired. diarrhoea. a sore or red tongue, sometimes with mouth ulcers. problems with memory, understanding and judgment (cognitive changes)
Vitamin B12 helps increase the body's production of melatonin, making it important for regulating sleep-wake cycles. Higher B12 levels have been associated with a lower risk of depression.
Low Blood Pressure
Deficiencies of vitamin B12 and folic acid can cause anemia, which can lead to low blood pressure, also known as hypotension. Vitamin B12 helps your body produce red blood cells so that adequate oxygen reaches each and every part of your body, including the heart.
Deficiency of Vitamin B12 can result in hematological changes, neurological and psychiatric problems, which can manifest as irritability, changes in personality, depression, and memory loss [9]. It is also known to worsen depression by excitotoxic reactions caused by the accumulation of homocysteine [10].
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Vitamin B12 testing requires a blood sample, which is usually taken from your arm in a medical office, health clinic, hospital, or lab. If you choose an at-home kit that screens for vitamin B12, you will receive the necessary supplies to take your blood sample.