Without magnesium present, Vitamin D is stored in the body and not used. The body depends on magnesium to convert Vitamin D into its active form within the body. Magnesium also helps Vitamin D bind to its target proteins, as well as helping the liver and the kidneys to metabolize Vitamin D.
If you are supplementing with vitamin D3, it's imperative you have enough magnesium to activate it. Why is this so important? Vitamin D3 cannot be utilized without sufficient magnesium; it simply remains stored in the body until it has enough magnesium to be activated.
A new review published in The Journal of the American Osteopathic Association found vitamin D can't be metabolized without sufficient magnesium levels, meaning vitamin D remains stored and inactive for as many as 50 percent of Americans.
Mg is essential in the metabolism of vitamin D, and taking large doses of vitamin D can induce severe depletion of Mg. Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.
Magnesium is needed to move vitamin D around in the blood and to activate vitamin D. Magnesium deficiency can also reduce active vitamin D (1,25 dihydroxyvitamin D) levels and impair parathyroid hormone response.
Dietary intake of magnesium is associated with reduced body mass index, waist circumference, body fat percentage, as well as inflammatory biomarkers and depressive symptoms. Vitamin D deficiency has been linked to inflammation, obesity, and depressive symptoms.
Magnesium and vitamin D3
Magnesium and vitamin D3 supplements can be taken together to ensure that the body functions adequately. Magnesium is important for the body to make vitamin D3 absorbable, and enzymes in the liver and kidneys require magnesium to break down vitamin D3.
Therefore, conditions that affect the gut and digestion, like celiac disease, chronic pancreatitis, Crohn's disease, and cystic fibrosis, can reduce vitamin D absorption.
Magnesium deficiency is diagnosed via a blood test and sometimes a urine test. Your doctor may order the blood test if you have symptoms such as weakness, irritability, abnormal heart rhythm, nausea and/or diarrhoea, or if you have abnormal calcium or potassium levels.
“Adding an over-the-counter vitamin D supplement can make improvements in just three to four months time.
Refining or processing of food may deplete magnesium content by nearly 85%. Furthermore, cooking, especially boiling of magnesium-rich foods, will result in significant loss of magnesium. The processing and cooking of food may therefore explain the apparently high prevalence of low magnesium intake in many populations.
Some side effects of taking too much vitamin D include weakness, dry mouth, nausea, vomiting, and others. Taking vitamin D for long periods of time in doses higher than 4000 IU (100 mcg) daily is possibly unsafe and may cause very high levels of calcium in the blood.
MAGNESIUM+VITAMIN D3 does not generally cause any side effects. In rare cases, it may cause side effects such as mild loss of appetite, nausea and fatigue. Most of these adverse effects do not require medical attention and will resolve gradually over time.
Use vitamin D cautiously if you're taking drugs processed by these enzymes. Digoxin (Lanoxin). Avoid taking high doses of vitamin D with this heart medication. High doses of vitamin D can cause hypercalcemia, which increases the risk of fatal heart problems with digoxin.
People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.
You can test your magnesium levels by purchasing a simple at-home finger prick test kit which is then analysed at an accredited lab. Forth offers a number of blood tests which include magnesium such as our Nutri-check test and Menopause Health blood test.
Drugs. Drugs such as oral steroids and diuretics also limit the absorption of vitamin D in the body. If you're deficient in vitamin D, you should avoid the consumption of certain foods because they can also make vitamin D absorption difficult or impossible in your body.
If you take too much supplemental or prescription vitamin D, it can lead to vitamin D toxicity. The main complication of this is moderate to severe hypercalcemia, which can cause symptoms like vomiting, increased thirst and frequent urination.
Magnesium assists in the activation of vitamin D, which helps regulate calcium and phosphate homeostasis to influence the growth and maintenance of bones. All of the enzymes that metabolize vitamin D seem to require magnesium, which acts as a cofactor in the enzymatic reactions in the liver and kidneys.
Magnesium helps support Vitamin D. Magnesium Citrate is a more bioavailable form to help activate vitamin D3 as per label. Vitamin D supports the immune cells and normal function of T & B cells, as per label. This supplement is quality guaranteed & made in the USA.