Without it, you can experience hormonal imbalances such as: Estrogen imbalance. A deficiency in vitamin D can lead to lower estrogen levels, which can cause depression, hot flashes, mood swings, and much more. Parathyroid hormone imbalance.
When vitamin D levels are extremely low in the body, the parathyroid gland is affected and usually tries to compensate by releasing more of the parathyroid hormone. This hormone normally deposits calcium into bone. Vitamin D causes calcium to be absorbed from the gut into the bloodstream.
A Fred Hutchinson Cancer Research Center study involving postmenopausal, overweight, and obese women who took 2,000 IUs of vitamin D daily for a year found that those whose vitamin D blood levels increased the most had the greatest reductions in blood estrogens, which are a known risk factor for breast cancer.
In addition, estrogen increases the activity of the enzyme responsible for activating vitamin D (34) and so declining estrogen levels during the menopausal transition could lead to symptoms of vitamin D deficiency.
The researchers discovered that using vitamin D supplements significantly reduced TSH mean levels, emphasizing the need for screening and vitamin D treatment in subclinical hypothyroid individuals [99].
Furthermore, it was reported that patients with Hashimoto's thyroiditis, an autoimmune thyroid disease had lower vitamin D levels. Vitamin D plays an essential role in calcium homeostasis and the development and maintenance of the skeleton.
Meta-analysis and case control study-based observations show that individuals with low vitamin D levels also have an increased risk of developing thyroid cancer [45]. In our study, we found a significant association between body mass index and hypothyroid state.
Estrogen imbalance: Vitamin D deficiency may lead to lowered estrogen levels, which can cause depression, hot flashes, mood swings and more. Impaired immune system: Vitamin D deficiency may lead to an impaired immune system, putting women at an increased risk of infection and illness.
These women were all given an extremely high dose of vitamin D (24,000 IU per week!) and it was found that this supplement was capable of lowering their progesterone levels by 10% and their oestrogen levels by 3%.
You can become deficient in vitamin D for different reasons: You don't get enough vitamin D in your diet. You don't absorb enough vitamin D from food (a malabsorption problem) You don't get enough exposure to sunlight.
Vitamin D is actually a hormone that communicates with your other hormones, making it especially essential to help balance hormones. So, ensure you're getting enough vitamin D2 and D3 to ease and prevent hormonal fluctuations.
Vitamin D may affect breast cancer development through several mechanisms of action. Among other things, it controls normal breast cell growth, decreases cancer cell growth, has anti-inflammatory effects and decreases the conversion of androgens (male hormones) to oestrogens, reducing serum oestrogen levels.
Parathyroid hormone increases the activity of the enzyme (catalyst) that produces active vitamin D. This increase in the concentration of calcium together with vitamin D feeds back to the parathyroid glands to stop further parathyroid hormone release.
In its active form, vitamin D increases progesterone and estrogen levels, maintains a healthy uterine lining, and reduces the risk of developing polycystic ovary syndrome and endometriosis. In men, vitamin D plays a role in the healthy development of sperm and maintenance of semen quality.
Vitamin D actively fights depression by increasing serotonin, the hormone key to stabilising mood and increasing happiness.
Having inadequate levels of vitamin D may correlate with unintentional weight gain. A study on women over the age of 65 found that participants with a lower vitamin D level experienced more weight gain.
There really is a link between Vitamin D and Testosterone. One large-scale study showed a 30% increase in Total T after taking Vitamin D. Some data has even shown that just sunlight can increase Testosterone.
Medical conditions that can cause vitamin D deficiency include: Cystic fibrosis, Crohn's disease and celiac disease: These conditions can prevent your intestines from adequately absorbing enough vitamin D through supplements, especially if the condition is untreated.
A negative and significant correlation was found between PTH and 25(OH)D levels in the present study. Individuals with low vitamin D levels were those who had higher values of PTH, while individuals with high values of vitamin D showed low values of PTH.
Vitamin D deficiency is very common in women of reproductive age which may affect menstrual cycle length due to a pronged follicular phase causing delayed ovulation.
Some studies indicated that vitamin D deficiency is associated with various autoimmune diseases [9]. Today, Hashimoto is one of the most common acquired hypothyroidism and autoimmune disease in children and adults [10]. The onset of autoimmune-thyroid disease with vitamin D deficiency is very common [11].
Risk of developing vitamin D deficiency in Hashimoto's
The levels of vitamin D deficiencies depend on the severity and degree of hypothyroidism. For example, as the severity of hypothyroidism increases, the more significant the amount of vitamin D deficiency happens in patients with Hashimoto's disease.
No interactions were found between levothyroxine and Vitamin D3. However, this does not necessarily mean no interactions exist.
Inadequate intake of iodine impairs thyroid function and results in a spectrum of disorders. Other common deficiencies of micronutrients such as iron, selenium, vitamin A, and possibly zinc may interact with iodine nutrition and thyroid function.