The cause of lymphoma is not fully understood. The risk of developing lymphoma can be increased by: A weakened immune system from conditions such as an inherited immune disorder or an autoimmune disease. Taking medicines that suppress your immune system.
Lymphoma is more common in people with immune system diseases or in people who take drugs that suppress their immune system. Developing certain infections. Some infections are associated with an increased risk of lymphoma, including the Epstein-Barr virus and Helicobacter pylori infection.
People between the ages of 15 and 40 and people older than 55 are more likely to develop Hodgkin lymphoma. Gender. In general, men are slightly more likely to develop Hodgkin lymphoma than women, although the nodular sclerosis subtype is more common in women (see the Introduction).
Lymphomas can start anywhere in the body where lymph tissue is found. The major sites of lymph tissue are: Lymph nodes: Lymph nodes are bean-sized collections of lymphocytes and other immune system cells throughout the body, including inside the chest, abdomen, and pelvis.
Blood tests may detect issues like having a high white blood cell count that may be a sign of lymphoma, leukemia or other blood cancers. But they don't detect lymphoma. Healthcare providers diagnose lymphoma based on biopsy and imaging tests results.
While the cause of the initial mutation that triggers non-Hodgkin lymphoma is unknown, a number of factors can increase your risk of developing the condition. These include having: a medical condition that weakens your immune system, such as HIV.
NHL is a disease that usually comes on suddenly and gets worse quickly. Symptoms vary depending on where tumor(s) are. These are the most common locations and their symptoms: Abdomen – pain, swelling, fever, anemia, tiredness, weight loss, vomiting, diarrhea, constipation, and irregular periods.
The goal of Hodgkin lymphoma treatment is to cure the disease. More than 80 percent of all patients diagnosed with Hodgkin lymphoma can be cured by current treatment approaches. The cure rate is higher, approaching 90 percent, in younger patients and those with early-stage favorable disease.
The most common symptom of Hodgkin lymphoma is one or more enlarged (swollen) lymph nodes. The enlarged lymph node may be in the neck, upper chest, armpit, abdomen or groin. The swollen lymph node is usually painless.
There is no evidence that suggests stress causes lymphoma or other types of cancer. Researchers cannot provide evidence that psychological stress worsens lymphoma in humans, either. That said, some members have shared that stress can affect how they experience lymphoma and its side effects.
Low-Grade Lymphoma
These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
Hodgkin lymphoma is a relatively aggressive cancer and can quickly spread through the body. Despite this, it's also one of the most easily treated types of cancer. Your recommended treatment plan will depend on your general health and age, because many of the treatments can put a tremendous strain on the body.
The 5-year survival rate for NHL in the United States is 74%. The survival rates for NHL vary based on several factors. These include the stage and subtype of cancer, a person's age and general health, and how well the treatment plan works. For stage I NHL, the 5-year relative survival rate is more than 86%.
Lymphoma is a cancer that starts in cells that are part of the body's immune system. Knowing which type of lymphoma you have is important because it affects your treatment options and your outlook (prognosis). If you aren't sure which type you have, ask your doctor so you can get the right information.
Burkitt lymphoma grows very rapidly, which means that symptoms usually develop quickly, over just a few days or weeks. The most common symptom is one or more lumps, which often develop in several parts of your body. These are swollen lymph nodes.
There is a chance that your treatment can increase the risk of getting another type of cancer in the future. This is because both chemotherapy drugs and radiotherapy work by damaging cells. They kill the lymphoma cells, but they can damage healthy cells too.
In practice, most people with high grade NHL have treatment as if it is an advanced cancer. This usually means quite intensive chemotherapy treatment with 3 or 4 different drugs, over 6 to 8 months.
Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia.
This is a rare, slow-growing type of lymphoma. It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured. But people can live with it for many years.
extreme tiredness – tiredness that doesn't go away even after rest or sleep (fatigue) chest pain, cough or breathlessness if there's a swelling in your chest. feeling uncomfortably full or feeling sick caused by a swelling in your stomach area. itching either widespread or in one place.
Blood tests are not used to diagnose lymphoma, but they can sometimes help determine how advanced the lymphoma is.
The most common sign of lymphoma is a lump or lumps, usually in the neck, armpit or groin. These lumps are swollen lymph nodes, sometimes known as 'glands'. Usually, they're painless. Fatigue is different to normal tiredness.
Certain areas of skin may also thicken, harden and form plaques that itch and ulcerate. Typically, these plaques develop on the face or buttocks or within skin folds. As a skin lymphoma rash progresses, papules (small bumps) may start to appear.
Lymphoma most often spreads to the liver, bone marrow, or lungs. Stage III-IV lymphomas are common, still very treatable, and often curable, depending on the NHL subtype. Stage III and stage IV are now considered a single category because they have the same treatment and prognosis.
Lymph nodes can swell for a variety of reasons and are considered to be enlarged if they are bigger than 1.5 centimeters in diameter, or slightly larger than a pea. Typically, lymph nodes that are enlarged due to lymphoma are much bigger and can grow to be the size of a grape (or larger).