Most people have symptoms of RA between ages 30 and 60, but men are unlikely to be diagnosed under age 45. 2 Across both men and women, the median age of onset is 58. RA can be categorized as young-onset rheumatoid arthritis (YORA) and later-onset rheumatoid arthritis (LORA).
RA usually starts to develop between the ages of 30 and 60. But anyone can develop rheumatoid arthritis. In children and young adults — usually between the ages of 16 and 40 — it's called young-onset rheumatoid arthritis (YORA).
It's possible to live a long life with RA, but it is estimated that the disease can potentially reduce life expectancy by 3 to 10 years.
RA can begin at any age, but the likelihood increases with age. The onset of RA is highest among adults in their sixties. Sex. New cases of RA are typically two-to-three times higher in women than men.
Rheumatoid arthritis is an autoimmune condition, which means it's caused by the immune system attacking healthy body tissue. However, it's not yet known what triggers this. Your immune system normally makes antibodies that attack bacteria and viruses, helping to fight infection.
Lupus and Scleroderma
The autoimmune diseases systemic lupus erythematosus and scleroderma often present with joint involvement that mimics rheumatoid arthritis. While lupus and scleroderma are two different diseases, they often overlap with one another.
Many people can live a healthy, active life with RA. For example, disease-modifying antirheumatic drugs (DMARDs) have become an effective and widely available medication for people with RA. These drugs work by suppressing the immune system and minimizing the damage that it does to joint tissue.
In a few people with RA -- about 5% to 10% -- the disease starts suddenly, and then they have no symptoms for many years, even decades. Symptoms that come and go. This happens to about 15% of people with rheumatoid arthritis. You may have periods of few or no problems that can last months between flare-ups.
Over the years, studies have shown that RA can shorten lifespan by an average of about ten years, the cause for this decrease is due to multiple factors, and there is an increasing impetus of managing other factors aside from physical disability and improvement of quality of life.
RA is a chronic condition with no known cure. People do not die from RA. However, it can lead to serious complications that can compromise overall health. A person with RA may have a reduced life expectancy.
RA is a very serious autoimmune disease, in which your immune system mistakenly attacks your own body's tissues and causes severe joint pain, stiffness, severe fatigue, and sometimes deformity, usually in the hands, shoulders, knees, and/or feet.
Bone erosion and destruction of cartilage can happen quickly within the first two years that you have rheumatoid arthritis, and the damage may continue to develop over time.
Stage I: Synovitis
During stage I, you may start having mild symptoms, including joint pain and joint stiffness. Most commonly, this affects the hands and fingers, as well as the ankles and knees. The immune system has begun attacking the joint tissue, causing the synovial membrane to swell and become inflamed.
Although there's no cure for rheumatoid arthritis, early treatment and support (including medicine, lifestyle changes, supportive treatments and surgery) can reduce the risk of joint damage and limit the impact of the condition.
Blood tests
No blood test can definitively prove or rule out a diagnosis of rheumatoid arthritis, but several tests can show indications of the condition. Some of the main blood tests used include: erythrocyte sedimentation rate (ESR) – which can help assess levels of inflammation in the body.
Vitamin D can play a role is easing some of the symptoms related to rheumatoid arthritis, but it is by no means a panacea. You still need your medication and other forms of therapy to keep the disease under control.
The longer you're exposed to stress, the more destructive the inflammation can become. In a PLoS One study, people with RA identified stress as a trigger for disease flare-ups. Arthritis symptoms contribute to stress, especially when they're unrelenting. Constant pain, fatigue, and poor sleep create a vicious cycle.
Many people with rheumatoid arthritis (RA) can silence their symptoms and halt progression of the disease thanks to biologics, targeted DMARDs and more aggressive treatment approaches. Yet some patients who achieve remission struggle to sustain it.
If rheumatoid arthritis is not treated early or is not well controlled, the inflammation in your joints could lead to significant and permanent damage. Problems that can affect the joints include: damage to nearby bone and cartilage (a tough, flexible material that covers the surface of joints)
RA can shorten your life expectancy by an average of 10 years compared to people who don't have the disease. But people with RA are living longer than ever before. Though the disease may still affect life expectancy, it doesn't have as much impact as it did in the past.
Lupus. When lupus, a systemic autoimmune disease, affects the joints, it can cause symptoms similar to RA. Most people with lupus also experience flares, where symptoms get worse, then improve or disappear. Other similar signs of lupus and RA include fatigue, fever, and dry eyes.
The main difference between osteoarthritis and rheumatoid arthritis is the cause behind the joint symptoms. Osteoarthritis is caused by mechanical wear and tear on joints. Rheumatoid arthritis is an autoimmune disease in which the body's own immune system attacks the body's joints.
For decades, X-rays were used to help detect rheumatoid arthritis (RA) and monitor for worsening bone damage. In the early stages of RA, however, X-rays may appear normal although the disease is active, making the films useful as a baseline but not much help in getting a timely diagnosis and treatment.