Donepezil (also known as Aricept), rivastigmine (Exelon) and galantamine (Reminyl) are used to treat the symptoms of mild to moderate Alzheimer's disease. Donepezil is also used to treat more severe Alzheimer's disease.
Four medications are currently available for the treatment of AD, and all were approved more than a decade ago. Of these, the first-line agents are the acetylcholinesterase (AChE) inhibitors donepezil, rivastigmine, and galantamine.
There is currently no "cure" for dementia. In fact, because dementia is caused by different diseases it is unlikely that there will be a single cure for dementia. Research is aimed at finding cures for dementia-causing diseases, such as Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies.
Keeping an active social life, regular exercise, and continuing activities the person enjoys, or finding new ones, can help to reduce behaviours that are out of character. Read more about activities for dementia. Other things that can help include: providing reassurance.
Comfort the person with verbal and physical reassurance. Distraction or redirection might also help. Giving your loved one a job such as folding laundry might help to make her feel needed and useful. People with dementia may become uncooperative and resistant to daily activities such as bathing, dressing, and eating.
Stay mentally and socially active. Engaging in mental or social activities may help to build up your brain's ability to cope with disease, relieve stress and improve your mood. This means doing these activities may help to delay, or even prevent, dementia from developing.
Over time, the disease causing the dementia spreads to other parts of the brain. This leads to more symptoms because more of the brain is unable to work properly. At the same time, already-damaged areas of the brain become even more affected, causing symptoms the person already has to get worse.
Terminal lucidity is not an official medical term, but it refers to people with dementia unexpectedly returning to a clear mental state shortly before death. Experts do not know exactly why a person may experience this lucidity, and more research on the neurological mechanisms involved is necessary.
The average life expectancy figures for the most common types of dementia are as follows: Alzheimer's disease – around eight to 10 years. Life expectancy is less if the person is diagnosed in their 80s or 90s. A few people with Alzheimer's live for longer, sometimes for 15 or even 20 years.
increasing confusion or poor judgment. greater memory loss, including a loss of events in the more distant past. needing assistance with tasks, such as getting dressed, bathing, and grooming. significant personality and behavior changes, often caused by agitation and unfounded suspicion.
On average, a person with Alzheimer's lives four to eight years after diagnosis, but can live as long as 20 years, depending on other factors. Changes in the brain related to Alzheimer's begin years before any signs of the disease.
Introduction: The five-word test (5WT) is a serial verbal memory test with semantic cuing. It is proposed to rapidly evaluate memory of aging people and has previously shown its sensitivity and its specificity in identifying patients with AD.
Aducanumab (Aduhelm™) has received accelerated approval as a treatment for Alzheimer's disease from the U.S. Food and Drug Administration (FDA).
Donepezil (also known as Aricept), rivastigmine (Exelon) and galantamine (Reminyl) are used to treat the symptoms of mild to moderate Alzheimer's disease. Donepezil is also used to treat more severe Alzheimer's disease.
Alzheimer's disease. This is the most common cause of dementia. Vascular dementia. This may occur in people who have long-term high blood pressure, severe hardening of the arteries, or several small strokes.
Many people affected by dementia are concerned that they may inherit or pass on dementia. The majority of dementia is not inherited by children and grandchildren. In rarer types of dementia there may be a strong genetic link, but these are only a tiny proportion of overall cases of dementia.
Dementia is likely to have a big physical impact on the person in the later stages of the condition. They may gradually lose their ability to walk, stand or get themselves up from the chair or bed. They may also be more likely to fall.
A 2019 study published in Journal of Alzheimer's Disease, showed among 165 participants (45 with diagnosed neurodegenerative disease, 120 controls) a supine sleep position (on back, head at body level) for more than 2 hours per night increased the risk of dementia by almost four times (3.7 times greater).
People with dementia think about the same things that any human thinks about — emotions, relationships, daily life, tasks to accomplish, and more. Receiving a life-changing diagnosis of dementia does not strip a person of their humanity and personhood.
The current evidence indicates that while chronic stress may play a role in the development or progression of dementia, it does not necessarily cause dementia. Hopefully, further research can begin to uncover what role stress plays in a person's risk of developing dementia.
For men and women with Alzheimer's disease or other forms of dementia, it can be especially beneficial. Watching movies and TV shows can help keep their brain active, which can stimulate positive memories, improve mood, and even increase socialization.
People living with dementia have the same emotional needs now that they did before the onset of dementia. They need opportunities to engage in meaningful activity, be free from anxiety and feel as though they still matter – especially during times of change or naturally stressful situations.
Often when a person with dementia asks to go home it refers to the sense of home rather than home itself. 'Home' may represent memories of a time or place that was comfortable and secure and where they felt relaxed and happier. It could also be an indefinable place that may not physically exist.