"Big Three" Infectious Diseases: Tuberculosis, Malaria and HIV/AIDS.
Tuberculosis remains one of the world's deadliest infectious diseases, second only to COVID-19, and drug resistant TB strains are still a major concern.
JUPITER, Fla. — Luiz Pedro Carvalho, Ph. D., is on a quest to find new medicines for treatment-resistant diseases, including tuberculosis, which is again the world's deadliest infectious disease, after briefly falling behind COVID-19.
The most deadly bacterial disease contracted by human beings is mycobacterium tuberculosis, the world's leading infectious disease with more than 1,700,000 deaths per year. As much as 13% of cases are resistant to most antibiotics, and about 6% are resistant or unresponsive to essentially all treatment.
cancer. dementia, including Alzheimer's disease. advanced lung, heart, kidney and liver disease. stroke and other neurological diseases, including motor neurone disease and multiple sclerosis.
Common viral illnesses include colds, the flu, COVID-19, norovirus (“stomach flu”), HPV (warts) and herpes simplex virus (cold sores). Many viruses go away on their own, but some cause life-threatening or chronic illnesses.
1. The Black Death: Bubonic Plague. The Black Death ravaged most of Europe and the Mediterranean from 1346 until 1353. Over 50 million people died, more than 60% of Europe's entire population at the time.
Cancer. Cancer refers to the uncontrolled growth of abnormal cells in the body. This can affect almost any organ or tissue including lungs, breast, colon, skin and ovaries. Due to the complexity of the disease and the variety of forms it can take, developing a cure has proven difficult.
Of the investigated pathogens, five—Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae, and Pseudomonas aeruginosa—accounted for 54.9% of the 7.7 million deaths, with S aureus associated with more than 1.1 million deaths.
Methicillin-Resistant Staphylococcus Aureus
This type of bacteria is resistant to many antibiotics, including methicillin. Most methicillin-resistant Staphylococcus aureus, or MRSA, infections contracted outside of a hospital are skin infections.
Some repeat infections, like pneumonia and bladder infections, may happen because of a genetic predisposition. That's an inherited tendency to get more infections than most people do. Structural issues. Repeat infections can also happen as a result of how your body is put together.
An infection can occur anywhere in your body. The most common places are: the mouth and throat. the skin.
Ischaemic heart disease was the leading single cause of deaths in Australia, responsible for 17,331 deaths in 2021, about one in 10 of total deaths that year. Males were more prone to the disease, accounting for 10,371 (59.8%) of the deaths compared to 6,960 (40.2%) for females.
Rabies. Rabies, one of the oldest known infectious diseases, is nearly 100% fatal and continues to cause tens of thousands of human deaths globally (1).
Cholera, bubonic plague, smallpox, and influenza are some of the most brutal killers in human history. And outbreaks of these diseases across international borders, are properly defined as pandemic, especially smallpox, which throughout history, has killed between 300-500 million people in its 12,000 year existence.
Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Infections that lead to sepsis most often start in the lung, urinary tract, skin, or gastrointestinal tract. Without timely treatment, sepsis can rapidly lead to tissue damage, organ failure, and death.
Many diseases and infections can be asymptomatic, including those that may be potentially fatal in some people. These include (but are not limited to): tuberculosis, breast cancer, endometriosis, HIV/AIDS, herpes, hepatitis, chlamydia, hypertension, common colds/flu, and type-2 diabetes mellitus.