Conclusions. Significant reductions in physical and metal fatigue for ME/CFS and Long-COVID patients were seen after 6 weeks of treatment. As there has been little progress in providing fatigue relief for the millions of ME/CFS and Long COVID patients, anhydrous enol oxaloacetate may bridge this important medical need.
Drug Therapies
Antidepressants often prescribed for chronic fatigue include: Tricyclics: amitriptyline (Elavil), desipramine (Norpramin), notriptyline (Pamelor) Selective serotonin reuptake inhibitors (SSRIs): citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft)
Central Nervous System Stimulants
Examples include modafinil (Provigil), armodafinil (Nuvigil), methamphetamine (Desoxyn), methylphenidate (Ritalin, Metadate), and amphetamine salts (Adderall).
Be sure to exercise at least four hours before going to bed, as exercise can also act as a stimulant and create restless sleep. Incorporate deep breathing exercises, massage therapy, meditation, yoga and muscle relaxation techniques into your daily routine as they can help manage symptoms of chronic fatigue syndrome.
Prozac, Paxil, Zoloft, Celexa, and Lexapro, are just a few brands of serotonin that we prescribe for those who suffer from depression, and/or anxiety disorder. There is evidence that these drugs can also improve premenopausal symptoms, even a role in the treatment of obesity and parkinson's disease.
Ritalin in the brain
Ritalin works by increasing the amount of dopamine released in the striatum, a key region in the brain related to motivation, action and cognition.
MDMA. MDMA, also known as Ecstasy or Molly, is a synthetic drug that produces a rush of euphoria and increased energy. It's commonly used in the club and rave scene, where people take it to enhance their enjoyment of music and social interaction.
Some researchers have reported that magnesium deficiency is common in people with chronic fatigue syndrome. Supplementing can help make up for a deficiency. NADH (nicotinamide adenine dinucleotide) helps make ATP, the energy source the body runs on.
Symptoms often worsen with physical or mental activity. In addition to severe fatigue, symptoms include light sensitivity, headache, muscle and joint pain, difficulty concentrating, mood swings, and depression. Treatments may include medicines, exercise, supplements, and counseling.
Some substances that produce feelings of euphoria include LSD, psilocybin, cocaine, methamphetamines, ecstasy (MDMA), ketamine, some benzodiazepines, heroin, codeine, fentanyl, and marijuana. 4. Medication-induced euphoric moods: Prescription medications may also produce euphoric effects.
Along with Celexa, Lexapro, and Xaxas, these medications — known as SSRIs, or selective serotonin reuptake inhibitors— enhance your mood by producing serotonin in the brain.
Prozac (fluoxetine) and Wellbutrin (bupropion) are examples of “energizing” antidepressants; whereas Paxil (paroxetine) and Celexa (citalopram) tend to be more sedating. Initial choices therefore, should be predicated on how the depression presents—as outlined in #2 above.
Serotonin and norepinephrine reuptake inhibitors (SNRIs)
Norepinephrine helps boost your energy levels and focus. So SNRIs can help stabilize your mood and make you feel more energized. The most common SNRIs prescribed to treat anxiety are venlafaxine extended-release (Effexor XR) and duloxetine (Cymbalta).
Vyvamind is one of the strongest energy pills on the market. Its ingredients are clinically proven to improve energy levels and reduce energy crashes. It also contains caffeine and L-Theanine, a substance that increases the functioning of mitochondria in the body.
Joy is the name of a series of psychoactive drugs used by the residents of Wellington Wells in order to forget bad memories and stay happy. The drug was created by Harry Haworth in 1953, upon commission from Robert Byng.
Most people with ME/CFS describe their fatigue as overwhelming and a different type of tiredness from what they've experienced before. Exercising usually makes the symptoms worse. Sometimes the effect is delayed and you'll feel very tired a few hours after you've exercised, or even the next day.
The original “happy pill” was fluoxetine, more commonly known as Prozac.
By the end of the 1960s, Valium was the top-selling psychotropic drug in the country. In the '70s, it became the most widely prescribed drug of any kind.
Escitalopram is thought to work by increasing the levels of a mood-enhancing chemical called serotonin in your brain. It usually takes 4 to 6 weeks for escitalopram to work fully. Common side effects include feeling sick (nausea) and headaches. They're usually mild and go away after a couple of weeks.