Lithium: The first
For roughly one-third of people diagnosed with bipolar disorder, lithium is a miracle drug, effectively treating both their mania and depression. But once someone is diagnosed, it can take up to a year to learn whether that person will be among the 30 percent who respond to lithium or the 70 percent who do not.
Relaxation techniques such as deep breathing, meditation, yoga, and guided imagery can be very effective at reducing stress and keeping you on an even keel. A daily relaxation practice can improve your mood and keep depression at bay. Make leisure time a priority.
Lumateperone (Caplyta) and Quetiapine (Seroquel, Seroquel XR) is used for the short-term treatment of bipolar depression. Another option is olanzapine (Zyprexa) with fluoxetine (Prozac). The atypical antipsychotic lurasidone (Latuda) can be taken alone or with lithium or valproate for treating bipolar depression.
Lamotrigine (Lamictal) for Bipolar Disorder
It is especially effective in the prevention of bipolar depression. It was the first FDA-approved therapy since lithium for maintenance in bipolar disorder.
Lithium helps reduce feelings of mania — excited, high mood, distracted. It also helps to treat bipolar episodes. Your doctor may prescribe lithium for long periods of time (months or years). It's important to continue treatment, even when you feel well.
Adverse effects were the most common cause for lithium discontinuation. Among the adverse effects, diarrhoea, tremor, creatinine increase, polyuria/polydipsia/diabetes insipidus and weight gain were the top five reasons for discontinuing lithium.
Bipolar disorder can cause your mood to swing from an extreme high to an extreme low. Manic symptoms can include increased energy, excitement, impulsive behaviour, and agitation. Depressive symptoms can include lack of energy, feeling worthless, low self-esteem and suicidal thoughts.
1. Mariah Carey. Singer, songwriter, actress and producer Mariah Carey has won too many awards to list. The iconic artist opened up in 2018 about her 2001 diagnosis of bipolar disorder, in which she was hospitalized for a physical and mental breakdown.
Magnesium: Magnesium — found in whole grains, beans, and dark leafy vegetables like spinach — has been shown to have an effect similar to lithium, the most common bipolar medication. Upping your intake of magnesium, a natural mood stabilizer, may decrease your need for medication.
The U.S. Food and Drug Administration (FDA) approved Rykindo as an extended-release injectable version of risperidone on January 15, 2023, according to a press release from Luye Pharma, the company that developed the drug.
The ones that treat bipolar depression are cariprazine (Vraylar), lurasidone (Latuda), olanzapine-fluoxetine combo (Symbyax), and quetiapine (Seroquel). Among them, lurasidone offers a good balance of efficacy and tolerability.
Lithium is not recommended in patients with renal impairment. It is also not recommended in patients with cardiovascular disease. Lithium causes reversible T wave changes and can unmask Brugada syndrome. A cardiology consult is necessary if a patient experiences unexplained palpitations and syncope.
A stressful circumstance or situation often triggers the symptoms of bipolar disorder. Examples of stressful triggers include: the breakdown of a relationship. physical, sexual or emotional abuse.
Using antidepressant medication alone to treat a depressive episode is not recommended in people with bipolar I disorder. The drugs may flip a person, particularly a person with bipolar I disorder, into a manic or hypomanic episode. Hypomania is a more subdued version of mania.
Bipolar disorder is frequently inherited, with genetic factors accounting for approximately 80% of the cause of the condition. Bipolar disorder is the most likely psychiatric disorder to be passed down from family. If one parent has bipolar disorder, there's a 10% chance that their child will develop the illness.
Call your doctor right away if you have diarrhea, vomiting, drowsiness, muscle weakness, tremors, unsteadiness, or other problems with muscle control or coordination. These may be symptoms of lithium toxicity.
Can I take lithium for a long time? Lithium is generally safe to take for a long time. Most people take it for years with no problems. If you've been taking lithium for some time, it can cause weight gain.
One of the side effects of lithium maintenance therapy is weight gain. Scientists believe that lithium-associated weight gain occurs due to various reasons, such as increased thirst, increased appetite, alterations in metabolism, sodium retention, hormonal fluctuations, constipation, and fatigue.