Zoledronic acid is an intravenous bisphosphonate. It is given as a once-yearly infusion for osteoporosis in patients aged 70 years of age or older with a bone mineral density T-score of –2.5 or less and in established osteoporosis with any fracture due to minimal trauma.
Zoledronic acid is given once a year as an intravenous (IV) infusion to treat osteoporosis. It is also given every two years as an IV infusion to prevent osteoporosis. Zoledronic acid increases bone density and reduces the incidence of the spine and non-spine fractures, including hip fractures.
The results of this trial indicate that a once-yearly infusion of zoledronic acid during a 3-year period significantly reduces the risk of vertebral, hip, and other fractures in patients with postmenopausal osteoporosis.
Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.
Romosozumab (Evenity).
This is the newest bone-building medication to treat osteoporosis. It is given as an injection every month at your doctor's office and is limited to one year of treatment.
Bisphosphonates. Bisphosphonates are a type of medicine that can slow bone loss, improve bone density and reduce the risk of fractures. Bisphosphonates are often the first type of medicine that doctors prescribe for confirmed osteoporosis in women who have been through menopause and men older than 50 years of age.
Weight-bearing exercises, such as walking, jogging, and climbing stairs, can help you build strong bones and slow bone loss.
Serious infections in your skin, lower stomach area (abdomen), bladder, or ear may happen. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia®.
Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.
You should not be treated with zoledronic acid if you are allergic to it. You also should not receive Reclast if you have: low levels of calcium in your blood (hypocalcemia); or. severe kidney disease.
User Reviews for Zoledronic acid to treat Prevention of Osteoporosis. Zoledronic acid has an average rating of 4.4 out of 10 from a total of 42 ratings for the treatment of Prevention of Osteoporosis. 31% of reviewers reported a positive experience, while 55% reported a negative experience.
Part B covers certain doctors' services, outpatient care, medical supplies, and preventive services. help pay for an osteoporosis injectable drug and visits by a home health nurse to inject the drug if you meet these conditions: You're a woman.
In a trial comparing Prolia to Fosamax, those taking Prolia showed a slightly greater improvement in bone density after one year. That's not to say Prolia is for everyone. Like Fosamax, it can occasionally lead to osteonecrosis of the jaw and atypical fractures.
The short answer is no, osteoporosis cannot be completely reversed and is not considered curable, but there are a number of health and lifestyle adjustments you can make to improve bone loss. Your provider may also prescribe you medications to help rebuild and slow down bone loss.
Just 30 minutes of exercise each day can help strengthen bones and prevent osteoporosis. Weight-bearing exercises, such as yoga, tai chi, and even walking, help the body resist gravity and stimulate bone cells to grow. Strength-training builds muscles which also increases bone strength.
Natural treatment of osteoporosis can include exercise, dietary changes, quitting smoking, and lowering alcohol caffeine intake. Supplementation of vitamin D and exposure to sunlight can also improve bone health. Such lifestyle changes may reduce the risk of osteoporosis and promote bone health and overall good health.
Preventing osteoporosis should begin in childhood, but no matter what your age, it's never too late to take steps to strengthen your bones.
You cannot reverse bone loss on your own without medications, but there are many lifestyle modifications you can make to stop more bone loss from occurring.
Types of Osteoporosis Medications
They include bisphosphonates, denosumab, estrogens, calcitonin, and others. Anabolic drugs increase bone formation. Examples are romosozumab (Evenity) and teriparatide (Forteo).
However, they are detrimental to bone health. Common examples of these drugs include tamoxifen (Nolvadex), femara (Letrozole), anastrozole (Arimidex), and exemestane (Aromasin). These can cause bone loss and bone fragility, predisposing patients to fractures.