Vitamin D toxicity might progress to bone pain and kidney problems, such as the formation of calcium stones. Treatment includes stopping vitamin D intake and restricting dietary calcium. Your doctor might also prescribe intravenous fluids and medications, such as corticosteroids or bisphosphonates.
Vitamin D can affect the liver function through the vitamin D receptor (VDR). VDR is naturally present in the liver cells and its higher expression can reduce inflammation in chronic liver diseases (Benetti et al., 2018). Vitamin D also has anti−fibrotic, proliferative, and inflammatory effects on the liver.
You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K.
CKD patients have greater requirements for some water soluble vitamins. Special renal vitamins are usually prescribed to kidney patients to provide the extra water soluble vitamins needed. Renal vitamins contain vitamins B1, B2, B6, B12, folic acid, niacin, pantothenic acid, biotin and a small dose of vitamin C.
Vitamin D has been reported to have a wide range of benefits. However, a recent case study indicates that excessive use of vitamin D can cause kidney damage in people who are not deficient in the vitamin. The article was published online April 8 in the Canadian Medical Association Journal.
Short-term vitamin D receptor activation increases serum creatinine due to increased production with no effect on the glomerular filtration rate.
In sum, multiple (but not all) studies have shown that low levels of 25(OH)D appear to be associated with a faster progression of kidney disease. In the KNHANES study, extremely low 25(OH)D levels in relatively healthy adults were associated with renal hyperfiltration, which likely causes further damage to the kidney.
But how do you flush vitamin D out of your system – and can you even do that? Yes, by ensuring you consume plenty of water. This will encourage urination, allowing your body to shed the excess vitamin D and calcium more quickly. Prescription diuretics like furosemide can also be helpful.
In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe.
For your kidneys to stay in the best condition possible, certain vitamins are essential. These vitamins are vitamin A, D, E, K, C, niacin, folic acid, B-complex vitamins, B5, and biotin. People with chronic kidney disorders can also take these vitamins to improve their health.
The kidney plays a pivotal role in vitamin D (VD) metabolism. In the proximal tubules the enzyme 1α hydroxylase (CYP27B1) transforms 25-hydroxyvitamin D into the active metabolite 1,25-hydroxyvitamin D (Figure 1). 25-hydroxyvitamin D (25VD) is absorbed in the proximal tubule cells via megalin-dependent pathway.
Outside of kidney function, several other factors can temporarily raise creatinine levels above normal. These include dehydration and consuming large amounts of protein — either through food sources or nutritional supplements. High intensity exercise can also increase certain blood biomarkers, including creatinine.
Many athletes and bodybuilders take supplements containing creatine to build muscle strength and endurance. The muscles use creatine for energy, but if the muscles do not use it, the body converts it into creatinine. This can result in high creatinine levels that doctors may misinterpret as kidney disease.
The recommended dietary allowance (RDA) of vitamin D for adults up to age 70 is 600 IU, with the RDA increasing to 800 IU above age 70. For those pregnant or breastfeeding, 600 IU is recommended.
There are quite a few differences between vitamin D and vitamin D3, but the main difference between them is that vitamin D is a fat-soluble vitamin that regulates calcium and phosphorous levels in the body, whereas the vitamin D3 is the natural form of vitamin D produced by the body from sunlight.
If you have CKD, your kidneys can't filter blood as well as they should, and this can lead to other health problems, such as heart disease and stroke. While it's not possible to reverse kidney damage, you can take steps to slow it down. Taking prescribed medicine, being physically active, and eating well will help.
Vegetables. Adding a variety of vegetables to your diet can help the body to fight against diseases. Bitter gourd, red bell pepper, cucumber and onions are some of the vegetables which help to regulate the levels of creatinine in the blood.