Paracetamol is a medicine used to treat mild to moderate pain. Paracetamol can also be used to treat fever (high temperature). It's dangerous to take more than the recommended dose of paracetamol.
Paracetamol belongs to the classes of analgesic and antipyretic drugs, commonly known as a pain reliever and fever reducer, respectively.
Paracetamol (acetaminophen) has central analgesic activity without a nonsteroidal anti-inflammatory drug (NSAID)-like or opioid-like effect.
Hazardous and harmful use
Paracetamol + Codeine contains the opioid Codeine and is a potential drug of abuse, misuse and addiction. Addiction can occur in patients appropriately prescribed Paracetamol + Codeine at recommended doses.
Opioids are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
Panadol products contain paracetamol; do not take them with other medicines that also contain paracetamol. Paracetamol is in many medicines to treat pain, fever, symptoms of cold and flu, and sleep medicines.
It's safe to take paracetamol with other types of painkiller that do not contain paracetamol, such as ibuprofen, aspirin or codeine. Do not take paracetamol alongside other medicines that contain paracetamol. If you take 2 different medicines that contain paracetamol, there's a risk of overdose.
If you take too much
Taking 1 or 2 extra tablets is unlikely to harm you. Do not take more than 8 tablets in 24 hours. Taking too much paracetamol can be dangerous and you may need treatment. Too much paracetamol can cause liver damage.
Adults (including the elderly) and children aged 16 years and over: Swallow 2 tablets with water, 20 minutes before you go to bed. Do not take more than 2 tablets in 24 hours. Do not take Panadol Night if you have already taken 4 doses of a paracetamol-containing product during the day.
Because ibuprofen has a strong anti-inflammatory effect, it is more effective than paracetamol at controlling certain types of pain, including rheumatoid arthritis, period pain, and muscular injuries.
While both medicines are safe, paracetamol has fewer risks associated with it among groups of people such as the elderly, and those with kidney disease or prone to gastrointestinal bleeding. If you're pregnant, paracetamol is also the safest choice.
Paracetamol is a commonly used medicine that can help treat pain and reduce a high temperature (fever). It's typically used to relieve mild or moderate pain, such as headaches, toothache or sprains, and reduce fevers caused by illnesses such as colds and flu.
Panadol Extra with Optizorb provides 37% stronger pain relief as compared to standard paracetamol alone1. It has been proven to be more superior in relieving pain across a number of pain states.
constipation • nausea • vomiting • stomach pain • dizziness • drowsiness • skin rashes • sweating. These are the more common side effects of Paracetamol/Codeine GH 500/30. They are usually mild.
The most powerful pain relievers are opioids. They are very effective, but they can sometimes have serious side effects. There is also a risk of addiction. Because of the risks, you must use them only under a doctor's supervision.
Ibuprofen has the highest liver safety profile among NSAIDs and showed no severe liver injury in larger studies. Along with paracetamol and aspirin, it is considered one of the most common over the counter NSAIDs sold in the world. Coxibs have currently replaced several NSAIDs due to safer GI profile.
Abuse of paracetamol can cause damage on your liver, while abuse of ibuprofen can cause damage to your stomach or liver. It's safer to take paracetamol if you are pregnant than ibuprofen. (In the case of the latter, you should consult your doctor first, but completely avoid it in your 3rd trimester)
Acetaminophen is generally considered safer than other pain relievers. It doesn't cause side effects such as stomach pain and bleeding.
It's safe to take ibuprofen with paracetamol or codeine. But do not take ibuprofen with similar painkillers like aspirin or naproxen without talking to a pharmacist or doctor.
What is the strongest anti-inflammatory medication? Research shows diclofenac is the strongest and most effective non-steroidal anti-inflammatory medicine available.10 Diclofenec is sold under the prescription brand names Cambia, Cataflam, Zipsor, and Zorvolex.
Long-term use of paracetamol may also cause heart problems. The systematic review of eight observational studies showed that four found a heightened risk, ranging from 19 to 68 percent, of cardiovascular problems.
Drug induced liver injury (DILI) is a common cause of acute liver injury. Paracetamol, also known as acetaminophen, is a widely used anti-pyretic that has long been established to cause liver toxicity once above therapeutic levels.
You should take the lowest dose that helps your pain. If you're still in pain after taking paracetamol for 3 or 4 days, speak with your doctor. Long-term use of paracetamol may increase the effect of warfarin. This can increase your chance of bleeding.