People of all races get keloids. Findings from studies, however, suggest that Black people have the greatest risk of developing keloids. People of Asian, Latin American, or Mediterranean descent are more likely to develop keloids than people who have a lighter skin tone.
Trauma, foreign-body reactions, infections, and endocrine dysfunctions have all been proposed as risk factors for the development of keloids after surgery in genetically susceptible people [1,2].
While keloids have the potential to develop in nearly anyone, some groups of people are at an increased risk of developing these skin features. Gender does not play any role in a person's likelihood of developing keloid scars. However, individuals with darker skin are at an increased risk.
Moreover, there is clinical evidence that patients with darker skin are 15 times more likely than patients with lighter skin to develop pathological scars (primarily keloids) [10]. Moreover, these scars are absent in albinos [11].
After the wound heals, apply silicone gel sheets or silicone gel. You can buy both of these products without a prescription. They can help prevent a keloid. To get the best results, you apply a new sheet or gel to the area every day.
Keloids are a type of raised scar that occurs on the skin after an injury heals. Keloids develop when scar tissue continues to form after the skin healing process ends. They are more common in people of African, Asian, and Hispanic descent.
Dark-skinned individuals form keloids 15 times more frequently than do their lighter-skinned counterparts. In both black and Hispanic populations, the incidence of keloid formation is as high as 16%, with higher frequencies during puberty and pregnancy.
This benign skin disease can either occur sporadically, or can exhibit a familial pattern. Keloid disease is considered a genetic disease due to a strong genetic susceptibility to keloid formation as it occurs predominantly in people of African and Asian descent, runs in families, and has been found in twins.
Some keloids can grow very large and may restrict movement or rub against clothing. However, the biggest concern for most people with keloids is cosmetic. The growths can be unattractive and may appear on the face, ears or other visible area of the body.
It can happen if you have too much of a substance called collagen in your skin. It can happen after any sort of injury or damage to your skin such as a cut, burn, surgery, acne or a body piercing. You're more likely to get a keloid scar if you: are of south Asian, Chinese, African Caribbean or Black African origin.
People with darker skin, such as black, Hispanic, and Asian people, are 15 to 20 times more likely to get keloids. But, some people with lighter skin also get them.
Most keloids continue to grow for weeks or months after they appear. A few grow for years. Growth tends to be slow.
How common are keloids? About 10 percent of people experience keloid scarring. People under the age of 30 may be particularly at risk. People of African, Asian, or Latino descent, pregnant women, and those with a family history of keloids are more susceptible to this type of scarring.
Keloid is considered a fibroproliferative disorder of skin wound healing, and its pathophysiological mechanisms are not fully known. As keloid only occurs in humans in which the psychological chronic stress component is already demonstrated, it is now also reported from the “psychomediation” perspective.
Results: Spontaneous keloids have been reported mainly in association with syndromes such as Rubinstein-Taybi syndrome, Dubowitz syndrome, Noonan syndrome, Goeminne syndrome, Bethlem myopathy, conjunctivocorneal dystrophy, X-linked recessive polyfibromatosis and a novel X-linked syndrome with flamin A mutation.
Conclusion: Keloids never completely disappear to leave skin with normal texture, however they can resolve (flatten and soften) so they no longer burden patients in approximately one third of cases. Scars resolving spontaneously do so early in the disease. Those that don't may resolve after many years of treatment.
Clinical Appearance of Keloids
They appear generally 3–9 months posttrauma, extend far beyond the area of a pustule or shaving injury, and do not spontaneously regress. They generally continue to grow over years and possibly decades.
From a population standpoint, two genome-wide association studies have identified four single-nucleotide polymorphisms (SNPs) across three loci that are associated with keloid formation. These three loci are found on chromosome bands 1q41, 3q22. 3–23, and 15q21. 3 (Nakashima et al., 2010, Zhu et al., 2013) (Table 2).
It is still unclear why some people are more likely to develop keloids rather than regular scars, but it seems that the longer a wound takes to heal, the greater the risk a person has of developing an overgrowth of scar tissue. Other things that may increase your risk include the following: A family history of keloids.
Darker-skinned individuals and those of African descent are mostly affected [3] . Even total African village population can be affected with familial keloid but in Indian population it is uncommon to find a case of familial keloid.
The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models. Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders.
Keloids and Hypertrophic Scars Can Now Be Treated Completely by Multimodal Therapy, Including Surgery, Followed by Radiation and Corticosteroid Tape/Plaster.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent.
Keloids are the result of excessive collagen production.