Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Common leukemia signs and symptoms include: Fever or chills. Persistent fatigue, weakness. Frequent or severe infections.
Leukemia can produce a variety of symptoms, although most are not often apparent in the earliest stages of the malignancy. The most common symptoms of leukemia—fatigue, pale skin, weight loss and night sweats—are often attributed to other less serious conditions, such as the flu.
Some people with leukemia or myelodysplastic syndromes have bone or joint pain. This bone pain is most often felt in the long bones of the arms and legs, in the ribs and in the breastbone.
Stage 1 – A patient has high levels of white blood cells and enlarged lymph nodes. Stage 2 – A patient has high levels of white blood cells and is anemic. He or she may also have enlarged lymph nodes. Stage 3 – A patient has high levels of white blood cells and is anemic.
Many people don't have any symptoms for at least a few years. In time, the cells can spread to other parts of the body, including the lymph nodes, liver, and spleen.
Physical exam: Your healthcare provider will ask about your symptoms and feel for swollen lymph nodes and an enlarged spleen or liver. They may also inspect your gums for bleeding and swelling. They may look for a skin rash associated with leukemia that may appear red, purple or brown.
Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. Leukemia* symptoms vary depending on the type of leukemia. Not everyone gets the same symptoms, and you won't necessarily have all of the symptoms. Most people with these symptoms won't have leukemia.
Causes of leukaemia
The cause of acute leukaemia is unknown, but factors that put some people at higher risk are: exposure to intense radiation. exposure to certain chemicals, such as benzene. viruses like the Human T-Cell leukaemia virus.
The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older. However, most cases of acute lymphocytic leukemia (ALL) occur in people under 20 years old. The median age of an ALL patient at diagnosis is 15.
Unlike symptoms of the flu, which generally subside as patients get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising. Other early warning signs of leukemia include: Fever, chills. Fatigue, weakness.
During the progression of leukemia, white blood cells (neoplastic leukocytes) found in bone marrow may begin to filter into the layers of the skin, resulting in skin lesions. “It looks like red-brown to purple firm bumps or nodules and represents the leukemia cells depositing in the skin,” Forrestel says.
Leukemia bruises have several distinguishing features that set them apart from normal bruises including: Location: Bruises may appear in places you would normally not have bruising, such as the back, chest, or face. Number: You may have many bruises at once, arising for no apparent reason.
How Is Leukemia Treated? Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.
Bone marrow exam
A bone marrow biopsy is often done at the same time. This second procedure removes a small piece of bone tissue and the enclosed marrow. Doctors may find chronic leukemia in a routine blood test, before symptoms begin.
Other oral symptoms of leukemia
swollen or painful gums. pale gums or paleness inside the mouth. an overgrowth of gum tissue around the teeth, which may cause the shape or size of the teeth to change in appearance. sores or injuries in the mouth.
Here is a list of some symptoms you might have if you have cancer related fatigue: lack of energy – you may just want to stay in bed all day. feeling you just cannot be bothered to do much. sleeping problems such as unable to sleep or disturbed sleep.
6. Is leukemia curable if caught early? If caught early, leukemia can be cured by undergoing several cancer treatments.
Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually.
Who gets leukemia? Although it is often thought of as a children's disease, most cases of leukemia occur in older adults. More than half of all leukemia cases occur in people over the age of 65.