Multiple sclerosis, rheumatoid arthritis, and polymyalgia rheumatica are three types of autoimmune disorders that affect the joints or nerves.
Rheumatoid arthritis, or RA, is an autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body. RA mainly attacks the joints, usually many joints at once.
Whipple's disease is rare and can mimic rheumatoid arthritis. Especially patients with seronegative rheumatoid arthritis with a prolonged disease course and insufficient treatment response should be reevaluated for Whipple's disease.
Asherson's syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.
Vasculopathy, skin ulcers, interstitial lung disease. Fever, systemic inflammation, panniculitis, lipodystrophy, hepatosplenomegaly, myositis.
Rheumatoid arthritis can be one of the most painful types of arthritis; it affects joints as well as other surrounding tissues, including organs. This inflammatory, autoimmune disease attacks healthy cells by mistake, causing painful swelling in the joints, like hands, wrists and knees.
Sudden pain in all the joints can be a symptom of several conditions, including infections, gout, ME/CFS, and some autoimmune conditions. It can also be an indication of complications after an illness, such as post-viral syndrome or reactive arthritis.
Osteoarthritis, the most common form of arthritis, involves the wearing away of the cartilage that caps the bones in your joints. Rheumatoid arthritis is a disease in which the immune system attacks the joints, beginning with the lining of joints. Arthritis is the swelling and tenderness of one or more joints.
Osteoarthritis is a disease of the joints. The two bones of a joint are normally protected by smooth, cushioning material called cartilage. In osteoarthritis, cartilage breaks down, causing pain and stiffness in the joint. Osteoarthritis is one of the most common forms of arthritis.
Rheumatoid arthritis is an autoimmune disease. Normally, your immune system helps protect your body from infection and disease. In rheumatoid arthritis, your immune system attacks healthy tissue in your joints. It can also cause medical problems with your heart, lungs, nerves, eyes and skin.
The most common viruses causing arthritis and/or arthralgias are parvovirus, the alphaviruses, hepatitis B, hepatitis C, Epstein-Barr virus (EBV), and tropical viruses, such as Zika and chikungunya (CHIKV).
Some common autoimmune diseases, including Type 1 diabetes mellitus, are relatively easy to diagnose, while others, such as vasculitis, Addison's disease, lupus, and other rheumatic diseases, are more difficult. Additionally, many of the 100-plus autoimmune diseases are uncommon or rare.
Whipple disease is a rare bacterial infection that most often affects your joints and digestive system. Whipple disease interferes with normal digestion by impairing the breakdown of foods, and hampering your body's ability to absorb nutrients, such as fats and carbohydrates.
Lupus can also cause inflammation in the joints, which doctors call “inflammatory arthritis.” It can make your joints hurt and feel stiff, tender, warm, and swollen. Lupus arthritis most often affects joints that are farther from the middle of your body, like your fingers, wrists, elbows, knees, ankles, and toes.
Fibromyalgia causes bodywide pain and extreme tiredness. It can be confused with arthritis because it may cause pain in joints, muscles and soft tissues.
Osteoarthritis, or degenerative joint disease, is a chronic, long-term illness. According to the CDC, osteoarthritis is a disease of the whole joint involving the cartilage, joint lining, ligaments and underlying bone. These tissues break down, leading to pain and stiffness in and around the joint.
Trigeminal neuralgia (TN), also known as tic douloureux, is sometimes described as the most excruciating pain known to humanity. The pain typically involves the lower face and jaw, although sometimes it affects the area around the nose and above the eye.
Rheumatoid Arthritis (RA) is a chronic, autoimmune disorder and is the most debilitating form of inflammatory arthritis. In RA, the body's immune system attacks its own healthy cells and tissues, specifically the synovial (joint lining) membrane, causing pain, swelling, stiffness, and limited joint mobility.
RPI Deficiency
This is considered to be the rarest disease in the world. Ribose-5-Phosphate Isomerase (RPI), is a crucial enzyme in a metabolic process in the human body. This condition can cause muscle stiffness, seizures, and reduction of white matter in the brain.
Ivemark syndrome is a rare disorder that affects multiple organ systems of the body. It is characterized by the absence (asplenia) or underdevelopment (hypoplasia) of the spleen, malformations of the heart and the abnormal arrangement of the internal organs of the chest and abdomen.
Takayasu arteritis is a rare autoimmune disease. It causes redness and swelling (inflammation) of the large arteries.