Plenty of fluid should be consumed while taking Hiprex. Your doctor may recommend drinking additional water and/or certain fruit juices (e.g., cranberry, plum, prune) and increased protein in the diet while taking Hiprex to ensure adequate hydration and acidity of the urine.
Avoid most fruits (especially citrus fruits and juices), milk and other dairy products, and other foods that make the urine less acid. Also, avoid antacids unless otherwise directed by your doctor.
Notes for Professionals: Methenamine should theoretically not be administered concurrently with food or beverages that may alter urinary pH, such as milk products and most fruits.
You can take Hiprex with or without food, but should avoid using the following medications as they may make Hiprex less effective. Note: If you are taking any prescription medicines, please consult your health professional before taking Hiprex.
Drugs and Foods to Avoid
This medicine works best in acidic urine. Drinking cranberry juice will help keep urine acidic. Avoid foods that lower the acid in your urine, such as nuts or milk and other dairy products.
Hiprex works best in an acidic environment so consider taking vitamin-C which may help to increase the bladder's acidity levels.
Some products that may interact with this drug include: sulfonamide drugs (including sulfa antibiotics such as sulfamethizole), products that decrease the amount of acid in the urine (urinary alkalinizers such as antacids, sodium bicarbonate, potassium or sodium citrate, carbonic anhydrase inhibitors such as ...
Hiprex is a urinary antibacterial agent with a wide antibacterial spectrum covering both gram-positive and gram-negative organisms. Urinary antibacterial activity can be shown within 30 minutes of administration.
Taking higher than recommended doses of Hiprex may cause bladder irritation, painful or frequent urination, and bloody or pink urine.
Timing: It is best to take Hiprex with food such as with breakfast and dinner. Take each dose with a full glass of water. Take Hiprex regularly to prevent UTIs. Do not wait for symptoms.
Notes for Professionals: Methenamine should theoretically not be administered concurrently with food or beverages that may alter urinary pH, such as milk products and most fruits.
Bland foods – In general, foods for when you're sick are also appropriate when you're taking antibiotics. Plain or lightly salted crackers, peanut butter and non-citrus fruit are good choices. The BRAT diet (bananas, rice, applesauce, toast) can help with diarrhea from antibiotics.
Bananas and other high-fiber foods can be good for urinary tract health and preventing urinary tract infections (UTIs) by encouraging regular bowel movements and relieving pressure on urine flow.
Avoid most fruits (especially citrus fruits and juices), milk and other dairy products, and other foods that make the urine less acid.
If you find it particularly difficult to swallow them, the tablets may be crushed and taken with a drink of milk or fruit juice. If you accidentally take more Hiprex than you should you might be sick or see blood in your urine.
Hiprex is used to prevent ongoing or recurrent urinary tract infections (UTIs). It works by causing your pee (urine) to be acidic and in this way discourages the growth of bugs. It is not effective for the treatment of UTIs but may be considered for preventing UTIs.
Hiprex® (methenamine hippurate tablets USP) should be taken by the mouth as directed by your doctor. Take each dose with a full glass of water.
Keep taking this medication for the full time prescribed, even if you feel well. Skipping doses or stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection and make the bacteria more difficult to treat (resistant).
Methenamine hippurate tablets are most effective in an acidic environment. Ural Effervescent Powder is a urinary alkaliniser and will make your urine less acidic, thus compromising the effectiveness of the methenamine hippurate tablets.
Additionally, a number of common foods and drinks — artificial sweeteners, spicy foods, alcohol, coffee, acidic fruits, citrus, or caffeinated drinks — can irritate your bladder, and may worsen UTI symptoms — so you should steer clear of them if you have signs of a bladder infection.
Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis.
Bladder irritation and frequent urination
Large doses of methenamine hippurate (Hiprex) (higher than recommended) can cause bladder irritation, frequent and painful urination, protein in your urine, and blood in your urine. Take the medication exactly as it is prescribed.
Using methenamine together with lactobacillus acidophilus may decrease the effects of lactobacillus acidophilus when these medications are taken at the same time. To prevent or minimize the interaction, lactobacillus acidophilus should be administered at least 1 to 2 hours before or after methenamine.