It's best to take metformin tablets with, or just after, your evening meal to reduce the chance of getting side effects. Swallow your metformin tablets whole with a drink of water. Do not chew them. If you're taking metformin sachets, pour the powder into a glass and add water (about 150ml).
The administration of metformin, as glucophage retard, at bedtime instead of supper time may improve diabetes control by reducing morning hyperglycemia.
-It acts on intestines and reduces the absorption of sugar. To overcome these side-effects, it is better to take it with meals or just after finishing meals. This helps to reduce some of these side-effects. Thus, it is advisable to take metformin with meals or just after finishing meals.
Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the tablet or extended-release tablet whole with a full glass of water.
Besides, metformin ER has a slow absorption without a rapid peak in blood stream and this produces less side gastrointestinal effects [7–9]. The last, but not the least, advantage is to reduce glycemia in the early morning which ameliorates the glycemic control of patients.
You'll have more energy as your body uses insulin more efficiently. Common diabetes-related symptoms, such as blurry vision, being thirsty all of the time, or having to pee a lot, improve or disappear.
Swallow it with a drink of water. Follow the directions on the prescription label. Take this medicine before meals. It should be taken no earlier than 30 minutes before meals.
It's best to take metformin tablets with, or just after, your evening meal to reduce the chance of getting side effects. Swallow your metformin tablets whole with a drink of water.
As much as possible, avoid white bread, white rice, white pasta, candy, soda, desserts, and snacks like chips or crackers. Eating foods that can spike your blood sugar will not necessarily make the metformin not work, however, it will increase the burden it has to work against.
Other things to avoid while on metformin
corticosteroids, such as prednisone. blood pressure medication, such as amlodipine (Norvasc) anticonvulsants, such as topiramate (Topamax) and zonisamide (Zonegran) oral contraceptives.
Be sure to take it with meals to reduce the stomach and bowel side effects that can occur – most people take metformin with breakfast and dinner. Extended-release metformin is taken once a day and should be taken at night, with dinner. This can help to treat high glucose levels overnight.
immediate-release metformin tablets, you should take them twice daily with meals. Some people prefer to take their dose with breakfast and dinner. extended-release metformin tablets, you only need to take them once each day. And you should take your dose with your evening meal.
Taking metformin with a meal has been shown to decrease bioavailability of metformin. We hypothesized that taking metformin 30 min before a meal improves glucose metabolism.
How long does it take to work? Metformin does not instantly reduce blood sugar levels. The effects are usually noticeable within 48 hours of taking the medication, and the most significant effects take 4–5 days to occur. However, the timing depends on the person's dosage.
Taking metformin can cause vitamin B12 deficiency if you take it for a long time. This can make you feel very tired, breathless and faint, so your doctor may check the vitamin B12 level in your blood. If your vitamin B12 levels become too low, vitamin B12 supplements will help.
Metformin does not immediately lower blood sugar levels. Improvement in blood sugar levels may take place within one to two weeks, but it may take two to three months for significant changes to take place. Typically, the starting dose of metformin is prescribed at 500 mg twice daily with meals.
Metformin may reduce how rapidly the body breaks down caffeine. Metformin when consumed in combination with caffeine can enhance the effects and side effects of caffeine.
Under certain conditions, too much metformin can cause lactic acidosis. The symptoms of lactic acidosis are severe and quick to appear, and usually occur when other health problems not related to the medicine are present and are very severe, such as a heart attack or kidney failure.
The American Diabetes Association (ADA) also recommends metformin for some people with prediabetes. Generally, if you're prescribed metformin, you'll be on it long term. That could be many decades, unless you experience complications or changes to your health that require you to stop taking it.
Coming off medication in diabetes remission
Some people are able to stop taking diabetes medication like metformin, by putting their diabetes into remission. This means that blood sugar levels are in the non-diabetes range without needing any medication.
Metformin has two advantages over other diabetes drugs: There's less risk of your blood sugar level falling too low. It doesn't cause weight gain.
Official answer. Metformin (brand name: Glucophage) will be in your system for 96.8 hours which is approximately 4 days. Metformin has an elimination half-life of approximately 17.6 hours.
Diabetics should avoid fruits with a high GI or eat them in moderation so that their blood sugar levels do not spike abruptly. Pineapple, watermelon, mango, lychee, and banana have a high GI, so these are the worst fruits if you are diabetic.
In general, for diabetes medications including oral hypoglycemic agents (e.g., metformin) and insulin, if you miss one dose, take the next one as soon as you remember it. However, if you remember close to the time of the next dose, then skip it and take the next dose instead. Do NOT double the dose.