“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won't affect your sleep.
You can definitely opt for taking vitamin B12 supplements at night if that's what works best for you, although the natural energy-boosting abilities of vitamin B12 might be put to better use as you're starting the day.
Vitamin B12 works on the pineal gland, which is responsible for the production of melatonin. The vitamin helps increase the production of melatonin during the nighttime hours, as well as release it earlier, making it easier to fall and stay asleep.
Vitamin C (ascorbic acid) supplements.
Taking vitamin B-12 with vitamin C might reduce the available amount of vitamin B-12 in your body. To avoid this interaction, take vitamin C two or more hours after taking a vitamin B-12 supplement.
Fat-soluble and water-soluble vitamins
For example, although it's safe to take vitamin D with vitamin B12, it's not advisable, says Virgilio Sanchez, MD, a board certified family medicine physician at Conviva Care Center in Miami, Florida.
Vitamin B-12 has a big role in stabilizing your energy levels. It actually helps give you more energy, rather than making you tired. If you do notice feeling a little fatigued, even though you're regularly taking a B-12 supplement, it's likely a sign of something else that is out of the norm in your body.
B12 also plays a role in the production of melatonin, a hormone that helps regulate our circadian rhythms. It is possible that a deficiency of B12 could lead to disrupted sleep patterns. Vitamin B12 also helps in the production of energy.
It's best to take vitamin B12 in the morning away from food to maximize absorption, as certain nutrients can inhibit it. However, vitamin B12 can be taken with food. Just ensure you're not dealing with any nutrient interactions.
So does vitamin B12 give you energy? While B12 doesn't directly provide energy, it does give the body the tools it needs to convert food molecules into energy. Getting the recommended daily amount of B12 can therefore help ensure that the body is able to make the energy it needs to do everything you need it to do.
Comparing the sublingual method to vitamin B12 injections, research found that taking B12 under the tongue had a higher absorption rate, making it a better option (Bensky, 2019). Taking vitamin B12 sublingually may also be a good option for people with a condition called pernicious anemia.
Vitamin B12
According to health experts at Click Pharmacy, as a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.
Since B12 shots are injected intramuscularly bypassing the digestive process, they start to work immediately. Typically, our patients experience positive effects between 24-72 hours after the treatment.
Vitamin B12 is considered an important brain and nervous system micronutrient and is often used for anxiety. It helps to ensure normal function for your nerves, which can help combat physical symptoms of anxiety.
Vitamin B12 is essential for the production of red blood cells and DNA. It is also essential for the functioning of the nervous system. When your body does not receive enough vitamin B12 you may feel fatigued and tired all the time. It can also lead to weakness.
Vitamin B12 is often used to improve cognitive function, depressive symptoms, and fatigue.
It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. If you have hydroxocobalamin injections to boost your vitamin B12 levels at the start of treatment, the cyanocobalamin tablets may start to work within a few days.
Fatigue. Megaloblastic anemia due to vitamin B-12 deficiency may lead to a person feeling fatigued. Without enough red blood cells to carry oxygen around their body, a person can feel extremely tired.
Vitamin B-12 and other B vitamins play a role in producing brain chemicals that affect mood and other brain functions. Low levels of B-12 and other B vitamins such as vitamin B-6 and folate may be linked to depression.
Can I take magnesium and vitamin B together? Yes, as B vitamins and magnesium don't compete for absorption inside your body. Indeed, many supplements combine them as a way of simplifying how you monitor your intake.
Regardless, research has indicated that a vitamin B12 deficiency can negatively affect those living with hypothyroidism, and that both deficiencies can go unnoticed if the proper tests are not performed.