While genetics is thought to play a role in Parkinson's, in most cases the disease does not seem to run in families. Many researchers now believe that Parkinson's results from a combination of genetic and environmental factors, such as exposure to toxins.
Parkinson's disease is caused by a loss of nerve cells in the part of the brain called the substantia nigra. Nerve cells in this part of the brain are responsible for producing a chemical called dopamine.
Medical experts believe that environmental causes may help trigger Parkinson's disease. Exposure to farming chemicals, like pesticides and herbicides; Vietnam-era exposure to Agent Orange; and working with heavy metals, detergents and solvents have all been implicated and studied for a clearer link.
The main risk factor is age, because Parkinson's disease is most commonly found in adults over the age of 50 (although diagnoses can occur in much younger people). Men also have a higher risk of Parkinson's disease than women.
Research suggests that stressful life events may increase the risk of Parkinson's disease. In addition, animal studies indicate that stress damages dopamine cells, resulting in more severe parkinsonian symptoms. In humans, acute stress can worsen motor symptoms, including bradykinesia, freezing, and tremor.
Individuals with PD may have a slightly shorter life span compared to healthy individuals of the same age group. According to the Michael J. Fox Foundation for Parkinson's Research, patients usually begin developing Parkinson's symptoms around age 60 and many live between 10 and 20 years after being diagnosed.
Tremors, muscle stiffness and slowness of movement are all common early symptoms of Parkinson's – but there are also other signs to be aware of. Sleep and night-time problems are common in Parkinson's.
Because the cause of Parkinson's is unknown, there are no proven ways to prevent the disease. Some research has shown that regular aerobic exercise might reduce the risk of Parkinson's disease.
Multiple system atrophy – the cousin of Parkinson's disease. MSA is a degenerative brain disorder that impairs the body's functions, including blood pressure, heart rate, bladder function and is related to Parkinson's disease.
Some studies have reported that the average time from onset of Parkinson's to developing dementia is about 10 years. One large study found that about three-quarters of people who live with Parkinson's for more than 10 years will develop dementia.
So far, only two theories have shown to be helpful: exercise and diet. According to studies, physical activity is not only a good way to treat patients with Parkinson's disease, it appears to help prevent or delay the onset. Getting the body moving helps build strength, balance, endurance and coordination.
The finger tapping test evaluates bradykinesia, focusing on decrement in rate, amplitude, or both with repetitive action. Vertical positioning of the hands during this task may also be clinically relevant.
Years can pass before symptoms are obvious enough to make a person to go to the doctor. There's no 'one size fits all' when it comes to Parkinson's disease — different people will experience different symptoms, and of varying severity. One in 3 people, for example, won't experience tremor.
In most cases, symptoms change slowly, with substantive progression taking place over the space of many months or years. Many people with PD have symptoms for at least a year or two before a diagnosis is actually made. The longer symptoms are present, the easier it is to predict how a person with PD will do over time.
If you suspect you have Parkinson's, you should see a movement disorder specialist, who is a neurologist with specialized training in Parkinson's and other movement disorders. On examination, the doctor looks for slowness, stiffness and resting tremor — the movement symptoms of Parkinson's.
What does kill people with Parkinson's? Falls – Parkinson's patients are typically at an increased risk of falls due to postural instability and other symptoms of Parkinson's.
When patients reach stage five – the final stage of Parkinson's disease – they will have severe posture issues in their back, neck, and hips. They will require a wheelchair and may be bedridden. In end-stage of Parkinson's disease, patients will also often experience non-motor symptoms.
Myth 5: Parkinson's disease is fatal.
Parkinson's disease is not a direct killer, like stroke or heart attack. That said, much depends on the quality of your care, both from your medical team and yourself. As the disease progresses, you may become more vulnerable to falls, which can be dangerous.
Parkinson's disease (PD), like most common disorders, involves interactions between genetic make-up and environmental exposures that are unique to each individual. Caffeinated-coffee consumption may protect some people from developing PD, although not all benefit equally.
Pseudobulbar affect (PBA) is characterized by frequent, uncontrollable outbursts of crying or laughing. It happens when a nervous system disorder, such as PD, affects the brain areas controlling expression of emotion. This disrupts brain signaling and triggers the involuntary episodes.
Though mild to moderate alcohol use does not increase the risk of Parkinson's, heavy drinking may. People with Parkinson's may develop worsening associated symptoms, such as depression or sleep issues, when consuming alcohol.
Vitamin C is essential for the brain development and has neuroprotective mechanisms for people with Parkinson's. Fruits rich in vitamin C include Cantaloupes, Oranges, Kiwi, Strawberries, raspberries, blueberries, and cranberries.