Low levels of B-12 and other B vitamins such as vitamin B-6 and folate may be linked to depression. Low levels of a vitamin can result from eating a poor diet or not being able to absorb the vitamins you consume.
Research suggests that certain nutrient deficiencies may put people at a higher risk of developing depression, including deficiencies in vitamins D, B12, and B9.
It has recently been discovered that taking high doses of vitamin B6 supplements significantly reduces feelings of stress, anxiety, and depression.
Mental health problems such as memory loss, anxiety, depression, irritability, and insomnia are also associated with deficiencies in vitamin B1. The brain uses this vitamin to help convert glucose or blood sugar into energy. This means that without it, the brain may not have enough energy to function normally.
Like vitamin D, vitamin B12 has so many mental benefits. Getting enough vitamin B12 may give you more energy, improve memory, and make learning new things easier. It also has been shown to help improve mood and lessen depressive symptoms.
“Vitamins B, C, and (water soluble) magnesium have been impactful for many who have anxiety and depression. It's important to remember that supplements and medications are proven aids at decreasing symptoms.
Some of the best vitamins for depression include vitamin D, iron, B9 (folate), calcium, vitamin C, and vitamins B12 and B3. Keep reading to learn more about vitamins that help with depression so you can make informed decisions about how best to treat your symptoms of depression.
The association between magnesium and depression has been observed in several studies. Some studies have found promising effects of magnesium supplementation in the treatment of depression. A 2017 study found that magnesium supplements improved symptoms of depression in adults.
Vitamin B deficiency (B1, B6, B7, B12, B complex) can contribute to depression, anxiety, and mood swings. It is associated with a disruption in the nervous system as well as the circulatory system. B12/B9, or folate, is at the forefront of mood management.
B-complex, vitamin E, vitamin C, GABA, and 5-HTP are 5 vitamins commonly used to help with anxiety and stress.
Recent findings: Low vitamin D levels are associated with increased symptoms of depression and anxiety. For this reason, vitamin D screening should be performed in the prevention and treatment planning of these mood disorders.
Studies that have reviewed the association between vitamin A and depression have suggested that retinoic acid, an active form of vitamin A, can cause depression and suicide in some susceptible individuals [24,25].
Very high daily doses of vitamin B12, ranging between 1000 and 2000 mcg, may effectively restore B12 levels within the body and positively impact depression symptoms. Even doses as low as 100 mcg are potent enough to positively impact cognition in adults with depressive symptoms.
Deficiency of Vitamin B12 can result in hematological changes, neurological and psychiatric problems, which can manifest as irritability, changes in personality, depression, and memory loss [9]. It is also known to worsen depression by excitotoxic reactions caused by the accumulation of homocysteine [10].
The lowdown. Medical research has linked magnesium to reduced anxiety. Magnesium helps you to relax by stimulating the production of melatonin and serotonin which boost your mood and help you sleep. Magnesium also reduces the production of cytokines and cortisol, which lead to increased inflammation and stress.
"Research has shown that magnesium supplementation may affect the brain functions that help lower stress and anxiety," Gorin says. It works by helping your body kick into the "rest and digest" state, or by activating your parasympathetic nervous system.
Vitamin B12
“B12 is essential for optimising our mood and mental performance, because it's essential for the production of serotonin,” says dietician Sophie Medlin. She explains that serotonin is our 'happy' hormone; the neurotransmitter that promotes feelings of wellbeing in our brain.
Recent studies show that foods with the highest antidepressant benefits include oysters and mussels, other seafood, lean organ meats, leafy greens, lettuce, peppers, and cruciferous vegetables such as broccoli, cauliflower, cabbage, kale, and Brussels sprouts.
Magnesium also modulates activity of the hypothalamic pituitary adrenal axis (HPAA) which is a central substrate of the stress response system. Activation of the HPAA instigates adaptive autonomic, neuroendocrine, and behavioral responses to cope with the demands of the stressor; including increasing anxiety.
Research still doesn't fully support taking magnesium for treating anxiety. This means that no minimum or maximum dosage is recommended specifically for anxiety. However, according to a 2017 review , the average doses used in studies ranged between 75 to 360 milligrams (mg) each day.
The best stress-relieving drinks include ginger, chamomile tea, valerian, black tea, coconut water, milk, green tea, coffee, lemon balm tea, water, and vegetable and fruit juice. Aromatherapy is another self-soothing practice shown to have benefits for mental health. You can read more about it here.