The differential diagnosis includes hypothyroidism, growth disorders, neoplasm, chromosomal abnormalities, and amyloidosis. Vitamin deficiencies, particularly Vitamin B12, cause B12 deficiency
Oral symptoms of Vitamin B12 deficiency may also include a swollen, beefy tongue, as well as burning sensations, discolorations and lesions throughout the mouth.
B12 deficiency will also make the tongue sore and beefy-red in color. Glossitis, by causing swelling of the tongue, may also cause the tongue to appear smooth.
A red tongue can be a sign of a vitamin deficiency (B2, B6, B9, B12) Iron deficiency, protein deficiency such as Kawasaki disease, or a strep infection (scarlet fever).
Many Vitamin B12 deficient patients experience mouth ulcers along with a burning and itching sensation in the mouth. Many others also suffer from Glossitis – this is a condition where the tongue changes colour and shape and appears red and swollen.
Anemia can cause symptoms in the mouth, such as a sore tongue and ulcers, but more commonly affects other aspects of a person's overall health.
Studies have found that vitamin D deficiency can lead to burning mouth syndrome, which is a painful condition that leads to a burning, scalding, or tingling feeling in the mouth, especially on the tongue.
Zinc deficiency can manifest as non-specific oral ulceration, stomatitis (painful mouth) or white tongue coating. Rarely, it can cause angular cheilitis (sores at the corners of the mouth) and burning mouth syndrome (mouth or tongue soreness). Smell and taste.
It is mainly characterized by an inflamed or swollen tongue in multiple shades of red. Other symptoms include the difficulty or inability to chew, swallow or speak, tongue pain or tenderness, and the loss of the papillae, or those bumps on your tongue that house your taste buds.
Riboflavin deficiency (sometimes called ariboflavinosis) causes stomatitis of the mouth and tongue, cheilosis (chapped and fissured lips) and a scaly rash on the genitalia.
Several commercially available test kits allow you to collect a sample for vitamin B12 testing at home. Some kits test only your vitamin B12 level. Others test B12 in combination with other vitamins, and there are at-home micronutrient test kits that include B12 in the panel.
Stage 1 is decreased levels of vitamin B12 in the blood. Stage 2 is low concentration of vitamin B12 in the cell and metabolic abnormalities. Stage 3 is increased levels of homocysteine and MMA and decreased DNA synthesis resulting in neuropsychiatric symptoms. Stage 4 is macrocytic anemia.
Overgrowth conditions such as Beckwith-Wiedemann syndrome and vascular anomalies of the tongue can lead to its enlargement. Other conditions such as Down syndrome, trauma, inflammatory conditions, primary amyloidosis, and congenital hypothyroidism may also be associated with a large tongue.
If you have macroglossia, your tongue may stick out of your mouth. You may also have trouble eating, breathing or talking. You can develop macroglossia if you have infections or certain cancers. If your child has macroglossia, these symptoms may be one of several caused by an underlying inherited condition.
Eye symptoms of low iron can include a pale coloring of the inside of the lower eyelids. In moderate or severe cases of iron deficiency anemia, the inside layer of the lower eyelid is very pale pink or yellow instead of red. Rather than low iron, one common cause of blurry vision is dry eye.
You may also find that low iron causes weight gain. There are a couple of reasons for this; firstly, your energy levels are low and so your exercise levels reduce; secondly, iron is essential for thyroid function, and an underactive thyroid will lead to weight gain.
People with zinc deficiency may also experience: hair loss. changes in their nails. diarrhoea.
The clinical manifestations in severe cases of zinc deficiency include bullous-pustular dermatitis, alopecia, diarrhea, emotional disorder, weight loss, intercurrent infections, hypogonadism in males; it is fatal if unrecognized and untreated.
(Rickets; Osteomalacia) Vitamin D deficiency is most commonly caused by a lack of exposure to sunlight. Some disorders can also cause the deficiency. The most common cause is lack of exposure to sunlight, usually when the diet is deficient in vitamin D, but certain disorders can also cause the deficiency.
Symptoms of Vitamin B6 Deficiency
In adults, vitamin B6 deficiency can cause inflammation of the skin (dermatitis) and a red, greasy, scaly rash. The hands and feet may feel numb and prickling—like pins and needles. The tongue may become sore and red, and cracks may form in the corners of the mouth.
Deficiencies in Vitamin A or riboflavin can also cause dry mouth.