Vitamins D, E + K Take these supplements at least two hours apart and with some sort of dietary fat to optimize absorption.
Some studies suggest that the body may not be able to absorb vitamin K as efficiently when taken with vitamins D and E. As a result, taking a large dose of these three vitamins together may prevent vitamin K from clotting the blood effectively [7].
Vitamin D, vitamin K2, and other fat-soluble vitamins
Research indicates the two fat-soluble vitamins (vitamin D and vitamin K2) work synergistically to ensure that calcium is absorbed by the bones rather than building up in your arteries. Fat-soluble vitamins, such as A, D, E, and K, can be taken at the same time.
Some vitamins that should not be taken together, or have dosage limitations, include vitamin C with vitamin B-12, vitamin A supplement with vitamin A-rich foods, folic acid (vitamin B9) and vitamin B12, and vitamin E with vitamin K.
Taking vitamins D, E, or K several hours before or after other fat-soluble vitamins would seem to maximize their absorption. Taking certain supplements with food can reduce gastrointestinal side-effects.
So, get enough vitamin D—just take it in the morning or afternoon. At night, take supplements that support sleep quality and muscle relaxation, like magnesium and melatonin (which you'll find in soothing, sippable Bulletproof Sleep Collagen Protein).
Certain medicines may interact with vitamin D and cause unbalanced levels in your bloodstream, so you should speak to your doctor before taking it as a supplement. Estrogen, isoniazid, and thiazide are three medications which may result in increased levels of vitamin D.
Can you take vitamin D and magnesium together? Yes. In fact, it's probably best to take both together. Because so many people have low magnesium levels, vitamin D supplements on their own aren't very helpful for a large portion of the population.
The short and simple answer is: Yes! Vitamins C and D are commonly found together in multivitamins. They have complementary effects, which means that taking them together can better support your health. They're particularly beneficial to the immune system.
Combining multiple supplements or taking higher-than-recommended doses can increase the risk that they can cause harm, said Kitchin.
Vitamin D and calcium are an important combo. Both are essential for the health of your bones. While some suggest that vitamin D on its own can support bone health, most studies examine its effect when paired with calcium.
Pair: Vitamin D + Calcium
Both nutrients are really important for bone health, so you'll likely want both regardless if you're looking to prevent poor bone health or need to supplement to build bone density back up. So, you might as well pair them together and take in one sitting, says Rizzo.
Vitamin D could also induce zinc transporters to regulate zinc homeostasis. Together, zinc and vitamin D in adequate concentrations help maintain a healthy musculoskeletal system and beyond; however, deficiency in either of these nutrients can result in various disorders affecting almost all body systems.
Can I take magnesium with other minerals and vitamins? Yes. Vitamins and minerals all work in combination and rely on each other to be fully effective. Taking magnesium helps your body to absorb and use minerals such as calcium, phosphorus and potassium, and vitamins like vitamin D.
When to take vitamin D. It just plain doesn't matter, as long as you take it with food, says Dr. Manson. Her advice: Take it when you'll remember to take it — morning, noon or night — and take it with a meal, she says.
Adequate levels of magnesium in the body are necessary for the absorption and metabolism of vitamin D, important for maintaining healthy bones and teeth and supporting the body's immune system, brain and nervous system.
Magnesium and calcium/multivitamin
Additionally, she says to refrain from taking calcium, magnesium or zinc together as they will “compete for absorption.” Click here to read the full article.
The Perfect Pair: KAL Magnesium Glycinate helps activate the action of Vitamin D, the “sunshine vitamin,” to support calcium absorption, strong bones muscle and immune health and more.
If you are wondering whether you are getting enough vitamin D3 to help fight off COVID-19, make sure you are also asking yourself if you are getting enough magnesium. A general rule of thumb is to take at least 100mg of magnesium per 1,000 IU of vitamin D3.
You can—but it's probably not a good idea. For some supplements, optimal absorption can depend on the time of day taken. Not only that—taking certain vitamins, minerals, or other supplements together can also reduce absorption and may result in adverse interactions, which can be harmful to your health.
A minimum of two hours is usually mandated, with some sources citing four to six hours as a minimum recommendation. For example, it is recommended that doses of calcium and levothyroxine be separated by at least four hours, because the former decreases the bioavailability of the latter.