Once you begin using Ozempic, some people can find it takes several weeks to see any weight loss, yet others may see some weight loss within a week or 2. While it can be difficult, try to remain patient — change looks different for everyone.
You may need a higher dosage of Ozempic
The same holds true for Ozempic's weight loss results. People taking higher doses of Ozempic tend to lose more weight. In the landmark study we cited above, people lost 7% of their body weight, on average, within a year and a half of taking 1mg of semaglutide.
Seeing results. Ozempic starts working within the first week of beginning your maintenance dose.
On average, a user can lose about 3 to 5% of their body weight after using Ozempic for a month regularly. This equates to about 4 to 6 pounds on average. Using a higher potency of the drug may result in more weight loss, but it isn't recommended that you start taking it right away.
How can I maximise my body weight loss on Ozempic? You can assist Ozempic by lowering your overall calorie intake, moving your body where possible and limiting your alcohol consumption.
Ozempic is also used off-label for weight loss. In particular, it can help reduce the amount of belly fat. This is because Ozempic works by making you feel fuller for longer, which can help you resist overeating by controlling cravings and hunger.
The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss. Semaglutide also helps the pancreas produce insulin, which is how it helps manage type 2 diabetes.
Study 1: Patients using Ozempic 0.5 mg dose lost on average 8 lb (3.6 kg), those using 1 mg dose lost 10 lb (4.5 kg), and those taking placebo (an inactive treatment) lost 3 lb (1.4 kg). Study 2: Patients using the Ozempic 1 mg dose lost on average 12 lb (5.5 kg), and those using the 2 mg dose lost 14 lb (6.3 kg).
Nausea was the most common side effect reported by people taking the drug in clinical trials. For most people, the nausea was mild and temporary. You're more likely to have nausea when you first start Ozempic treatment or after your doctor increases your dose.
It's used to lower blood glucose (sugar) levels in adults with Type 2 diabetes. The starting dose of Ozempic is 0.25 mg injected once weekly for 4 weeks. Then, your dose is moved up to 0.5 mg once weekly.
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
A 2022 study found that most individuals gain weight back a year after stopping the medication.
You should inject Ozempic once a week — on the same day of the week, every week. It doesn't make a big difference whether you take it in the morning or at night. It's possible to change the day of the week you inject Ozempic. The general rule is to avoid injecting it with less than 2 days in between shots.
It's important to note that if you start taking either of these drugs for weight loss, your body may get used to it, establishing a new normal. This can cause your weight to plateau. Research has shown that if you stop taking Ozempic (or Wegovy), it's likely that you will gain back the weight you lost.
For Ozempic, the peak time is about 2-4 days after the first dose and around 4 weeks after regular dosing. The peak time refers to the time at which the medication reaches its highest concentration in the body.
Can I enjoy a drink while on Ozempic medication? The short answer is yes: You can drink alcohol while taking Ozempic.
The good news is, there are no foods that you have to eat or have to avoid while taking Ozempic. Still, Ozempic and other GLP-1 medications will be most effective for weight loss and blood sugar control when combined with a healthy diet and regular exercise.
You may see some weight loss in the 4 weeks of semaglutide treatment, but the full effect can take several months. After 68 weeks, adults lost about 35 lbs (15.9 kg) in studies, on average. Your doctor will slowly increase your dose when you start treatment to help lessen stomach side effects like nausea and diarrhea.
It takes about two to four weeks to notice weight loss if you're consistently meeting your diet and exercise requirements. However, this is unique to every individual since there are many factors that determine how much weight you lose.
Patients trying to lose weight with either drug should work with a dietitian for a guided meal plan, but in general, they should aim to eat 1,200 to 1,800 calories a day depending on their initial weight, Rubin says.