Most people don't have side effects from statins, but you shouldn't take them if you're pregnant, nursing or have certain types of liver disease. Let your provider know if you have diabetes. If you're already at risk for diabetes, statins can add to your risk of getting it.
Statins should not be taken if you have liver disease or if blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a damaged liver.
Low-density lipoprotein (LDL) cholesterol.
If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L). If your risk is very high — for example, you've had a heart attack in the past — a statin may be helpful even if you don't have high cholesterol.
Which foods or drinks should be avoided while taking statin drugs? Grapefruit juice is the only food or drink that has a direct interaction with statins.
Fear of side effects and perceived side effects are the most common reasons for declining or discontinuing statin therapy. Willingness to take a statin is high, among both patients who have declined statin therapy and those who have never been offered one.
Statins shouldn't be taken if you have severe liver disease or blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a severely damaged liver.
If you've made lifestyle changes through diet and exercise that have lowered your cholesterol levels, you may not need to continue taking a statin. These changes can help reduce your risk of heart attack, stroke, or blocked arteries while allowing you to take one less medication.
Statin use is associated with increased calorie intake and consequent weight gain. It is speculated that statin‐dependent improvements in lipid profile may undermine the perceived need to follow lipid‐lowering and other dietary recommendations leading consequently to increased calorie intake.
We have data now from over 20 statin trials of over 135,000 patients that show statins compared with placebo or no medication result in a 23 percent reduction in heart attacks, 17 percent reduction in fatal or non-fatal stroke and 19 percent reduction in death from cardiovascular causes. So, they definitely work.
Total cholesterol levels should be lower than 5.5 mmol/L, if you have no other risk factors. If you have cardiovascular risk factors such as high blood pressure, pre-existing cardiovascular (heart) disease or diabetes, or you smoke, the aim for LDL cholesterol levels would be less than 2 mmol/L.
As a general guide, total cholesterol levels should be: 5mmol/L or less for healthy adults. 4mmol/L or less for those at high risk.
High cholesterol levels are considered: too high: between 5 and 6.4mmol/l. very high: between 6.5 and 7.8mmol/l. extremely high: above 7.8mmol/l.
After having their cholesterol tested, seniors should be given a number between 190 and 260. Healthy seniors should keep their total cholesterol below 200 and their LDL cholesterol around 100. If your elderly loved one's LDL cholesterol level is above 160, he or she must start making sweeping lifestyle changes.
So, why do people take statins at night? Many statins work more effectively when they are taken at night. This is because the enzyme which makes the cholesterol is more active at night. Also, the half-life, or the amount of time it takes for half the dose to leave your body, of some statins is short.
The use of statins may be connected to weight gain, but there's no clinical evidence as to why this weight gain occurs.
Side Effects of Statins: Risk Versus Benefit
Like all drugs, statins bring the risk of side effects. Muscle pain, liver damage, increased blood sugar, and fuzzy thinking are the most common – which can scare some candidates off.
Ezetimibe is a tablet that lowers cholesterol. It may be prescribed if statins cannot be taken, or alongside a statin for extra cholesterol-lowering. It's a 'cholesterol absorption inhibitor' that limits the absorption of cholesterol in the small intestine.
You usually have to continue taking statins for life because if you stop taking them, your cholesterol will return to a high level. If you forget to take your dose, do not take an extra one to make up for it. Just take your next dose as usual the following day.
If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.
Oatmeal, oat bran and high-fiber foods
Soluble fiber is also found in such foods as kidney beans, Brussels sprouts, apples and pears. Soluble fiber can reduce the absorption of cholesterol into your bloodstream. Five to 10 grams or more of soluble fiber a day decreases your LDL cholesterol.
One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be serious enough to make it hard to do your daily activities.