Even though the crossovers did not result in a clear winner,
Originally Answered: Could Darkseid solo the Marvel comics? Nope. Darkseid would get destroyed.
Phobia: Incredible as it may seem, Darkseid fears his father, Yuga Khan, more than anything else; Yuga Khan is the one being in the universe far more powerful and evil and was worse of a tyrant than even Darkseid.
There have been several versions of Hyperion over the years, but the most formidable is the one who joined the Avengers and helped them battle against threats like Thanos and the Beyonders. That Hyperion would be able to defeat Darkseid. Hyperion's power is even greater than Thor's, and he's just as skilled a fighter.
Thor would certainly be thwarted by Darkseid. This fearsome villain would be able to drain the lifeforce from him, and even his godly weaponry doesn't seem like it could withstand Darkseid's Omega Beams.
Thanos (copied from DC's Darkseid)
The Big Bad in the Marvel Cinematic Universe, Thanos, is actually an imitation of the Big Bad in the DC universe, Darkseid.
He is the arch-nemesis of Orion, his son, Highfather, Yuga Khan, Mister Miracle, the rest of New Genesis, the Justice League, and the whole DCU, especially both Superman and Wonder Woman, and is widely regarded as one of the DC Multiverse's most powerful and malevolent villains of all time.
History. During the invasion, Zeus held the axe while Ares prepared, and in the onslaught Ares used the axe to kill many parademons. While Darkseid was fighting Zeus, Ares landed a powerful blow to Darkseid, breaking the latter's spear and wounding his shoulder.
Physically, Darkseid stands two-feet taller than Thanos but in pure strength, it would be a very brutal, and, possibly, equal fight.
1 Darkseid Is Too Devastatingly Powerful For Captain Marvel
On a one on one basis, Darkseid would be able to beat her into submission. If he uses the Omega Effect, she would fall to it. Darkseid is just too much for Captain Marvel, as good as she is.
in a true lasting. way while Darkseid can just straight blink Ultron out of existence Ultron might be powerful. but he's definitely bit off more than he can chew with facing down the true Dark Side here Dark Side wins.
Superhuman Strength: Zeus is strong enough to go toe-to-toe with Darkseid in his weakened state.
Darkseid is a God. A sufficiently powerful person with a sword could kill Loki. The last time Darkseid died, in Final Crisis, it took a concerted effort by the entire superheroic community, and in death, his spirit still almost destroyed the DC Multiverse. Loki has nothing he could do to hurt Darkseid.
Tactical Advantage. Iron Man, Dr. Strange, and Hulk (in Banner form) might defeat the Justice League if they find a tactic to take Superman out. Like what's said above, a kryptonite gun might weaken Superman, and Thor could give a powerful blow to the head.
Tony Stark's abilities make him a powerful and worthy opponent, but not against Darkseid. Comic fans have asked if Thanos could defeat Darkseid several times, but ultimately the answer is always in favor of Darkseid.
But here's why the dark god suffered a humiliating defeat in the History Lesson. In Zack Snyder's Justice League's History Lesson, Darkseid suffered a humiliating defeat thousands of years ago, with the Greek God of War, Ares (David Thewis), nearly killing the lord of Apokolips.
To date, Suli is the only person that Darkseid has ever truly loved.
Created by Jack Kirby, radion is an element that can wound or even kill any of the New Gods, as Orion and Darkseid found out in DC's Final Crisis! While Superman is famously vulnerable to kryptonite, even that radioactive material doesn't have anything on the New Gods' radion - a substance that can even kill Darkseid.
While Darkseid is a deity and immortal, having lived for several hundred thousand years, he is not invincible and has been killed on several occasions. Darkseid is able to drain the life force of other godly beings to rejuvenate himself or return to his full power.
Weakness. Radion: Darkseid and all of the New Gods are vulnerable to a substance called Radion. It source is unknown and its effects are toxic only in sustained amounts or after explosive exposure. The average New God can be slain by an application of Radion from a Radion blaster or bomb.
A battle between the two would shake the heavens but Darkseid would win it.
Darkseid's perpetual rival is Highfather, the leader of New Genesis ― Apokolips's sister planet.
1 WOULD LOSE TO: Darkseid
While the Hulk's immense strength gives him as good a chance as anyone against Darkseid, Darkseid's Omega Beams would be the deciding factor. The Hulk may survive a blast or two from them, but the more he's hit with them the more of a toll they'll take.
Ghost Rider might be extremely powerful but going up against a villain of Darkseid's magnitude would spell trouble for him. Darkseid is as mighty as a god, and it seems that even with Ghost Rider's demon on his side, he wouldn't be an equal match.