Research now shows that high doses of oral vitamin B12 (eg. 1000mcg daily) can be just as effective at treating deficiency, even in the absence of intrinsic factor, and may be a suitable alternative to intramuscular injections for many people.
A. Low B12 can cause anemia and fatigue. For many people with low B12 levels, a daily supplement in the form of a pill is as effective as taking a monthly muscle injection.
Two studies used 1000 μg/day oral vitamin B12 and showed no relevant difference to intramuscularly applied vitamin B12 with regard to vitamin B12 blood levels. One trial used 2000 μg/day vitamin B12 and showed higher vitamin B12 blood levels in favour of oral vitamin B12.
Methylcobalamin is the most active form of vitamin B12 and, for best results, should be combined with adenosylcobalamin.
You need vitamin B12 to make red blood cells and keep your nervous system healthy. You'll usually take cyanocobalamin tablets every day to prevent or treat vitamin B12 deficiency. However, you may also need vitamin B12 injections at first to boost your levels.
How to raise your B12 levels fast. The most common way to treat B12 deficiencies is by adjusting your diet. If this is unsuccessful, vitamin supplements may be recommended. If you're looking to boost the amount of vitamin B12 in your diet, you should eat more animal products, like meat, seafood, dairy and eggs.
Hydroxocobalamin starts to work straight away. However, it may take a few days or weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. Are there any long-term side effects? It's OK to have hydroxocobalamin injections for a long time.
Safety and side effects
When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.
There are certain foods that also need a cut-down in case of vitamin B12 deficiency. “Some foods and drinks can interfere with vitamin B complex intake like alcohol, caffeine and processed foods, etc should be avoided completely,” Shah added.
If you do require a vitamin B12 supplement, follow this advice from our experts: ✔️ Seek out methylcobalamin. Most vitamin B12 supplements contain cyanocobalamin, which contain trace amounts of cyanide, Somer says. It's also far less efficient than supplements made with methylcobalamin.
It is common to experience headaches, dizziness, and weakness immediately after the injection. These should fade fairly quickly. You may also experience some numbness and tingling, depending on the injection location, as well as joint pain.
It increases energy levels and concentration, may improve metabolism, boosts the immune system, and aids in restful sleep. Since this vitamin is essential for DNA synthesis, nerve cell health, red blood cell formation, and neurological function, a vitamin B12 injection really is a no-brainer.
If you have had neurological symptoms that affect your nervous system, such as numbness or tingling in your hands and feet, caused by a vitamin B12 deficiency, you'll be referred to a haematologist and may need to have injections every 2 months.
[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer disease—such as proton-pump inhibitors, H2 blockers, or other antacids—may have difficulty absorbing vitamin B12 from food.
Bananas are a cheap, healthy, and nutrient-dense fruit that can easily become a part of every individual's diet. It is one of the best fruits rich in vitamin B12. Bananas also contain fibre and potassium. It helps manage blood pressure, reduce stress, and relieve constipation and ulcer problems.
Simply put, how long the B12 shot will last is different for everyone. Though it differs a bit from one person to another, the effects of B12 vitamins usually last around 48 hours to 72 hours after the initial injection.
Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.
There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.
Avoid alcohol for 48 hours after your treatment. Avoid strenuous exercise for 48 hours after your treatment. Avoid touching the injection site for 6 hours after your treatment. You may experience a dull ache at the injections site for around 1 hour after your treatment.
B12 injections work quickly. They are one of the most effective ways for your body to assimilate vitamin B12. Within 48 to 72 hrs, your body will begin making new red blood cells. For deficiencies, you may require a number of injections over a few weeks to see peak impact.
High doses of B12 were successful in bringing the subjects' sleep-wake cycles back into a normal range. This suggests that B12 has an influence over our circadian rhythm, however researchers are yet to determine the exact connection.
Patients with B12 levels between 200 and 300 pg/mL are considered borderline, and further enzymatic testing may be helpful in diagnosis. Patients with B12 levels below 200 pg/mL are considered deficient.
Key points about vitamin B12 deficiency anemia
Without enough red blood cells, your tissues and organs don't get enough oxygen. Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.