Based on current data, magnesium taurate and glycinate have the most research supporting their effects on anxiety and other mental health disorders. Magnesium malate and threonine have also demonstrated therapeutic effects and may be useful in many psychiatric cases.
Magnesium is an important mineral that helps maintain a healthy mood. Low levels of magnesium are associated with fatigue, anxiety, and depression. Research shows that adults, as well as children, don't get enough magnesium and that this may be linked to climbing rates of mood and mental health problems.
Only magnesium L-threonate has been shown to have a high affinity for the brain and have an effect on memory, learning, and cognitive function.
Magnesium citrate is a more common choice if you want to maintain magnesium levels for general whole-body health. On the other hand, magnesium glycinate has less bioavailability but can have a calming effect.
Magnesium citrate is one of the most absorbable types of magnesium, and that's why we use it in our Natural Calm® supplements. The magnesium in Natural Calm® is sourced from deep in the sea, and we combine it with natural citric acid from sugar beets to create a powder that dissolves easily in liquid.
Magnesium glycinate, which combines the mineral with the amino acid glycine, is the most popular and well-researched combination for treating sleep disorders and helping to reduce anxiety, depression, and stress.
Research still doesn't fully support taking magnesium for treating anxiety. This means that no minimum or maximum dosage is recommended specifically for anxiety. However, according to a 2017 review , the average doses used in studies ranged between 75 to 360 milligrams (mg) each day.
People who have kidney issues should consult a doctor before taking magnesium glycinate. Kidney problems can cause difficulties in excreting the excess magnesium.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
Some animal studies have found that magnesium threonate is more effective at increasing magnesium ions in the brain and improving cognitive function than magnesium sulfate. Therefore, doctors may recommend magnesium L-threonate to normalize an individual's magnesium levels and for potential benefits to the brain.
How long does it take for magnesium to reduce anxiety? In most cases, magnesium starts working within a week, since it's a fast-acting nutrient. You need to take it consistently to reduce anxiety and help you relax.
The benefits of magnesium supplementation in healthy individuals aren't clear, but Dr. Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.
If you're feeling overwhelmed, look to magnesium. One study showed magnesium intake reduces fear memory but enhances working memory, so you'll be more inclined to take healthy risks without overthinking.
Magnesium Puts The Breaks on the Intrusive Thoughts
In terms of neurotransmitters and mental health, magnesium inhibits the release of excitatory neurotransmitters and can increase feel good brain chemicals such as serotonin.
The association between magnesium and depression has been observed in several studies. Some studies have found promising effects of magnesium supplementation in the treatment of depression. A 2017 study found that magnesium supplements improved symptoms of depression in adults.
Magnesium effects the Hypothalamic–pituitary–adrenal axis in the brain, which controls the stress response system and therefore, anxiety and depression. Tentative data indicate that oral magnesium supplementation may be effective for treating mild to moderate adult depression.
Magnesium blocks the actions of glutamate in the NMDA receptors. If your body is magnesium deficient, it means that few of the NMDA receptors are blocked. This may lead to overexcitation and cell damage. Because of this, it is possible that magnesium may be useful in the treatment and prevention of depression.
Magnesium oxide and magnesium glycinate are common supplements of magnesium. Magnesium oxide has more magnesium per unit volume while magnesium glycinate has less amount of magnesium per unit volume; however, magnesium glycinate is better absorbed by the body than magnesium oxide.
Research has not identified a single type of magnesium that definitively treats anxiety. However, some forms are associated with tension relief and supporting brain balance. These are magnesium glycinate, magnesium threonate, and magnesium citrate.
Magnesium also modulates activity of the hypothalamic pituitary adrenal axis (HPAA) which is a central substrate of the stress response system. Activation of the HPAA instigates adaptive autonomic, neuroendocrine, and behavioral responses to cope with the demands of the stressor; including increasing anxiety.