Magnesium L-Threonate is an easily absorbed, extremely bioavailable form of magnesium, and is the optimum form for supporting brain and nervous system health.
In the nervous system, magnesium is important for optimal nerve transmission and neuromuscular coordination, as well as serving to protect against excitotoxicity (excessive excitation leading to cell death) [1,2].
Magnesium citrate is a more common choice if you want to maintain magnesium levels for general whole-body health. On the other hand, magnesium glycinate has less bioavailability but can have a calming effect.
Magnesium citrate is more gentle than some of the other magnesium compounds and found as the active ingredient in many commercially available laxatives. Magnesium is needed in order for muscles and nerves to function properly.
Based on current data, magnesium taurate and glycinate have the most research supporting their effects on anxiety and other mental health disorders. Magnesium malate and threonine have also demonstrated therapeutic effects and may be useful in many psychiatric cases.
Who should avoid magnesium citrate? Magnesium citrate may interact with drugs, including specific antibiotics and medications that doctors prescribe to lower calcium concentration in the urine, such as potassium or sodium phosphate. People on low-sodium or restricted-sodium diets should also avoid magnesium citrate.
People who have kidney issues should consult a doctor before taking magnesium glycinate. Kidney problems can cause difficulties in excreting the excess magnesium.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
While there are many forms of magnesium available, we often prefer to use magnesium citrate and/or magnesium glycinate. Magnesium citrate is most helpful for people suffering from constipation, while the glycinate form is more useful for conditions like anxiety, insomnia, chronic stress, and inflammatory conditions.
For best absorption, choose magnesium orotate, oxide or citrate. Too much: Tolerable upper limit (UL) = 350 mg.
Magnesium ion can promote peripheral nerve repair by inhibiting inflammation.
Magnesium decreases nerve pain. Clinical experience, as well as research in nerve pain conditions such as pancreatic cancer, has shown that magnesium can be an effective treatment for pain.
Generally speaking, you will find that magnesium supplements start to work after one week of using them. After one week of regular magnesium supplementation, individuals may experience benefits such as improved energy levels, reduced muscle cramps, better sleep quality, and reduced anxiety.
The key difference between magnesium and magnesium glycinate is that magnesium is a chemical element having the symbol Mg whereas magnesium glycinate is a chemical compound having the chemical formula C4H8MgN2O4.
Magnesium glycinate is known for its calming effects and is often used to promote relaxation and better sleep, says Fultz. It's best taken at night before bed.
Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin). Magnesium should be taken 1 hour before or 2 hours after taking these medications. Quinolone and tetracycline antibiotics include: Ciprofloxacin (Cipro)
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with MAGNESIUM. Magnesium might slow blood clotting. Taking magnesium along with medications that also slow clotting might increase the chances of bruising and bleeding.
Potential microbial contamination has prompted Vi-Jon LLC to recall a slate of branded magnesium citrate saline laxative products, many of which are under a Class I recall, according to the September 21, 2022, US Food and Drug Administration (FDA) Enforcement Report.