Bifidobacterium longum – Known to be a histamine degrading probiotic . It may help reduce the post-meal inflammatory response and prevent or improve intestinal hyperpermeability (“leaky gut syndrome”). Bifidobacterium lactis – May help break down histamine and tyramine.
It has been shown that probiotic bacteria are effective for the treatment of allergic diseases. As histamine plays a central role in allergic diseases, it is possible that probiotic bacteria affect the allergy-related histamine signaling.
Avoid these: Lactobacillus casei, Lactobacillus reuteri, and Lactobacillus bulgaricus. These strains produce histamines, and they're found in most yogurts and fermented foods.
Diamine oxidase (DAO) supplements are over-the-counter products that restore the diamine oxidase enzyme in your body. They help break down histamine-rich foods and may reduce symptoms of histamine intolerance. Research shows that these supplements might offer relief from headaches, digestive issues, and skin reactions.
Histamine neutral strains…
Lactobacillus acidophilus, Lactobacillus Lactis, Lactococcus Lactis, and Lactobacillus plantarum which do not have any effect on biogenic amines like histamine and tyramine.
Among the putative histamine-secreting bacteria in GTDB, five genera including Bacteroides, Clostridium, Bifidobacterium, Fusobacterium, and Lactobacillus are common in the human gut microbiota [29,30,31,32].
The authors identified Klebsiella aerogenes, present in the gut microbiota of many patients with IBS, as the main bacterial producer of histamine.
The best way to clear histamine from the body is to start an elimination diet that involves only eating and drinking substances that contain low amounts of histamine.
Claritin and Zyrtec are popular over-the-counter antihistamines. Doctors consider them safe and effective treatments for minor allergies. Both are second-generation antihistamines. These cause less drowsiness than first-generation antihistamines.
Vitamin C is a natural antihistamine, which means it can lower histamine levels and mitigate allergic reactions and symptoms. Consume plenty of Vitamin C rich foods, like tropical fruits, citrus fruits, broccoli and cauliflower, and berries.
Probiotics are one of the most essential supplements for healing histamine intolerance.
Some probiotics can produce histamine within the digestive tract. Those with histamine intolerance may want to avoid these strains of bacteria.
Histamine intolerance (HIT) is assumed to be due to a deficiency of the gastrointestinal (GI) enzyme diamine oxidase (DAO) and, therefore, the food component histamine not being degraded and/or absorbed properly within the GI tract.
Histamine is a chemical created in the body that is released by white blood cells into the bloodstream when the immune system is defending against a potential allergen. This release can result in an allergic reaction from allergy triggers such as pollen, mold, and certain foods.
Magnesium is key mineral that can help with histamine intolerance and mast cell activation and most people find that upping their magnesium intake can help with oral and gastric tolerance and reduce symptoms.
These include: Flushing, difficulty regulating body temperature, sudden excessive sweating. Hives, rashes, swelling, itchy skin, eczema. Racing heart, palpitations, arrhythmia.
You can block nighttime histamine release and get a better night's sleep by taking 0.25 -1 mg of ketotifen or zaditen at night.
In vivo studies have shown that the antral hormone gastrin is the main stimulus for acid secretion and histamine release. This hormone is released from gastrin (G) cells of the antrum after food uptake and binds to specific gastrin receptors on ECL cells (10, 25, 49, 62, 65, 70).
HIGH histamine: Besides allergens caused by mast cell degranulation, high levels of histamine can also be due to gut permeability by activating T cells in our body and food that contains high histamine.
Medications, such as certain painkillers (ibuprofen and morphine, among others), antibiotics and drugs for high blood pressure, can also release histamine. A vitamin B12 injection also releases (a lot of) histamine from the mast cells.
Because many sources of Vitamin C can actually raise your histamine levels. If you are dealing with Mast Cell Activation Syndrome or Histamine Intolerance, you want to avoid those forms of Vitamin C! These are some of the most common high histamine sources of Vitamin C to avoid: Ascorbic Acid in most forms – Why?
Bacterial overgrowth is another contributing factor for developing a histamine intolerance. Bacteria grows when food isn't digested properly, causing histamine overproduction. Normal levels of DAO enzymes can't break down the increased levels of histamine in your body, causing a reaction.
Summary. Natural antihistamines may help you control your seasonal allergies. Common ones are stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics. Some alternative practices—such as acupuncture, nasal irrigation, and exercise—may also help you manage symptoms.