Studies suggest that vitamin D3 increases tyrosinase activity and melanogenesis in vitro [12], which may lead to repigmentation in vitiligo skin lesions. Calcipotriol and tacalcitol, which are vitamin D analogs, are also known to induce repigmentation in patients with vitiligo [13,14].
Vitamin D decreases the expression of various cytokines that cause vitiligo. In conclusion, application of vitamin D might help in preventing destruction of melanocytes thus causing vitiligo and other autoimmune disorders.
Vitamin B12 has been shown to be useful for repigmentation in patients suffering from vitiligo. Folic acid (or vitamin B9) has been proven to be significant for treating vitiligo. It needs to be included in the diet as the body cannot synthesize it.
Deficiencies in calcium, vitamin D and vitamin E can cause white patches on the skin. While harmless, these white spots indicate that you need to eat a healthy, balanced diet.
Vitamin C is not used and is contraindicated in treating vitiligo as it disrupts the melanin production pathways [21]. Vitamin D is a fat-soluble vitamin that absorbs substances like calcium and magnesium.
A significant body of data suggests that vitamin D3 has a strong immunosuppressive activity and its low levels are associated with autoimmune conditions including vitiligo [6].
Vitamin D is known to enhance the rate of melanin synthesis; and this may concurrently regulate the expression of furin expression. In silico analyses have revealed that the intermediates of melanin are capable of binding strongly with the active site of furin protease.
“Adding an over-the-counter vitamin D supplement can make improvements in just three to four months time. Vitamin D with a strength of 1000-2000 international units daily is the recommended dose for most adults,” Dr. Ropte says.
Which vitamin is good for white spots on skin? -Vitamin B12 is essential for the production of melanin and is known to be effective in treating white spots on skin caused by vitiligo. Other vitamins such as Vitamin D and Vitamin C are also known to be beneficial for the skin.
Consuming 1,000–4,000 IU (25–100 mcg) of vitamin D3 daily should be ideal for most people to sustain good health. It is generally recommended that people with vitiligo keep their vitamin D levels in the mid-upper range of normal.
Vitamin B12 and Folic Acid
This is why it is always recommended to take these two vitamins together in order to treat vitiligo. According to some scientific studies, a combination of vitamin B12 and folic acid supplementation and sun exposure is a good strategy to regain natural skin color.
Light therapy.
Phototherapy with narrow band ultraviolet B (UVB) has been shown to stop or slow the progression of active vitiligo. It might be more effective when used with corticosteroids or calcineurin inhibitors. You'll need therapy two to three times a week.
4) Does vitamin D brighten skin? A. The cholesterol in your skin converts to vitamin D when it absorbs sunlight, and further helps make your skin and cells healthy and happy. This way, vitamin D helps in determining your skin tone and in turn, make it radiant and bright when exposed correctly.
Here's one possibility as to why: Vitamin D is known to reduce inflammation and inflammation is one of the causes of skin conditions, such as acne, eczema, psoriasis, rashes and more. Other research connects vitamin D as being important for skin cell growth, skin protection and supporting skin immunity.
Protect your skin from the sun.
A bad sunburn can worsen vitiligo. If you have a lighter skin tone, there's another advantage to protecting your skin from the sun. Without a tan, the lighter spots and patches are often less noticeable.
A meta-analysis of randomized controlled trials that compared the effects of vitamin D2 and D3 supplements on blood levels found that D3 supplements tended to raise blood concentrations of the vitamin more and sustained those levels longer than D2. [76,77] Some experts cite vitamin D3 as the preferred form as it is ...
There's no set time of day that's best to take vitamin D supplements. Some people say taking vitamin D supplements at night is an insomnia risk. There's no research to confirm this, but you might want to take your supplement earlier in the day if you think it's screwing with your sleep.
According to the National Institutes of Health, vitamin D promotes calcium absorption in the gut and helps regulate the concentration of calcium and phosphorus in the blood, which supports building and maintaining healthy, strong bones and helps regulate skeletal and neuromuscular function.
Use the CVS Health At Home Vitamin D Test Kit to get accurate and comprehensive results in the privacy and comfort of your own home. Simply collect your blood sample using this convenient kit, mail it to the lab, and receive your results through a secure online portal in just a few days.
The best food sources of vitamin D are oily fish, including salmon, mackerel, and sardines. Other sources include egg yolks, red meat, and liver. Vitamin D is added to some foods too, including breakfast cereals, plant milks and fat spreads. Check information on-pack to see if this applies to the products you buy.
Folic acid and vitamin B12 supplementation combined with sun exposure can induce repigmentation better than either the vitamins or sun exposure alone. Treatment should continue as long as the white areas continue to repigment.
Boosting your intake of vitamin A is the number one way to restore melanin in the skin. Taking daily supplements or eating animal and plant-based foods that contain this source of nutrient can be great resources. Some animal-based foods include whole or skim milk, eggs, cheese, and beef.