have ever had an allergic reaction to rosuvastatin or any other medicine. have liver or kidney problems. are trying to get pregnant, are already pregnant or are breastfeeding. have lung disease.
You should not take rosuvastatin if you are allergic to it, or if you have: liver disease; or. if you are pregnant or breast-feeding.
As you are aware, on March 4th of this year, we petitioned the FDA to ban the recently-marketed cholesterol-lowering drug rosuvastatin (Crestor/AstraZeneca) because of seven post-marketing cases of life-threatening rhabdomyolysis and nine cases of renal failure or renal insufficiency, both of which problems had also ...
Rosuvastatin is a medication that treats high cholesterol. It also reduces your risk of heart attack and stroke. It decreases bad cholesterol and fats and increases good cholesterol in your blood. A healthcare provider may recommend adding changes to your diet and exercise when taking this medication.
You may need to stop using this medicine if you have a major surgery, major injury, or if you develop other serious health problems. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have unusual tiredness or a fever.
Serious side effects
Stop taking rosuvastatin and call a doctor or contact 111 if: you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and kidney damage. This can happen a few weeks or months after you first start taking this medicine.
Muscle and Kidney Damage
The most common side effects for statin patients affect the muscles. Myalgia is the most common of the muscle-related side effects. The risk increases in patients 65 years and older. Patients with kidney impairment are also at an increased risk for myalgia.
A low-dose statin like atorvastatin (Lipitor®) is safe for most patients, including those with mild liver enzyme abnormalities.
If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.
If you forget to take a dose of rosuvastatin, take it as soon as you remember. If you do not remember until the next day, skip the missed dose and take your next dose at the usual time. Never take 2 doses at the same time. Never take an extra dose to make up for the forgotten one.
The FDA recommends rosuvastatin dosage reductions in Asian patients because pharmacokinetic studies have demonstrated an approximate two-fold increase in median exposure to rosuvastatin in Asian subjects when compared to Caucasian controls. Yet, no explanation for this ethnic difference has been confirmed.
Rosuvastatin is used to lower cholesterol if you have been diagnosed with high blood cholesterol. It's also taken to prevent heart disease, including heart attacks and strokes. Your doctor may also prescribe rosuvastatin if you have diabetes, kidney disease, or a family history of rheumatoid arthritis or heart disease.
Fear of side effects and perceived side effects are the most common reasons for declining or discontinuing statin therapy. Willingness to take a statin is high, among both patients who have declined statin therapy and those who have never been offered one.
Bempedoic acid (Nexletol), a cholesterol-lowering drug intended for people who can't or won't take statins, was shown to reduce the risk of heart attack by 23 percent, according to a late-breaking clinical trial recently presented at the American College of Cardiology Conference and published online March 4 in the New ...
High cholesterol levels are considered: too high: between 5 and 6.4mmol/l. very high: between 6.5 and 7.8mmol/l. extremely high: above 7.8mmol/l.
One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be serious enough to make it hard to do your daily activities.
Rosuvastatin reduces ambulatory blood pressure and increases nocturnal blood pressure decline when administered at bedtime apart from its lipid lowering effects. This blood pressure lowering effect may be related to improved endothelium dysfunction that use to be common at dyslipidemic subjects.
The use of statins may be connected to weight gain, but there's no clinical evidence as to why this weight gain occurs.
Statins are the most common medicine for high cholesterol. They reduce the amount of cholesterol your body makes.
Differences between individual statins have been found in their potency to reduce low density lipoprotein cholesterol (LDL-C) and achieve lipid-lowering goals in both randomized trials23–25 and observational studies. Rosuvastatin is known to induce a more marked reduction in LDL-C than other statins.
Atorvastatin or fluvastatin are usually recommended because there is no need to adjust the dose according to the glomerular filtration rate [28]. In patients without diagnosed atherosclerotic cardiovascular disease, it is indicated a moderate dose of statin, such as atorvastatin 20 mg daily [28].