Madara Uchiha was considered to be the strongest Uchiha clan member in Naruto when alive, and even after decades, he lived up to his name when he was resurrected.
Indra Otsutsuki is the founder of the Uchiha Clan. He was the elder son of Hagoromo Otsutsuki.
In conclusion, Obito Uchiha would defeat Itachi Uchiha when comparing the two characters in their strongest forms. Obito has one of the strongest, if not the strongest, Sage Mode in the series and has enough chakra reserve to beat Itachi.
Izuna Uchiha
Still, his Mangekyō abilities never reached their full potential and he tragically fell in battle at his rival's hands.
10 Could: Itachi Uchiha
Itachi was able to fight against Naruto Uzumaki in his Nine-Tails Chakra Mode, something that Pain could never do. He was also able to incapacitate Nagato Uzumaki, and it is quite easy to see that he could definitely have taken on and defeated Pain in combat.
Taking all things into perspective, Kakashi is unarguably one of the most complete shinobi in the entire Naruto series. Might Guy, on the other hand, lacks the ability to perform a Genjutsu for use strong Ninjutsu.
The Second Uchiha is a text-based character quest by RepThe21st where participants play as Uchiha Sasuke from the anime Naruto. The quest was started on Apr 20, 2015 on the forum Sufficient Velocity in the Quests category and is told in second person.
1 Kaguya Otsutsuki
She wields the Rinne-Sharingan, which is needed to cast the strongest Genjutsu in the entire series. With her Rinne-Sharingan, Kaguya can cast the Infinite Tsukuyomi over the entire world.
Obito Uchiha is one of the main antagonists of the Naruto franchise. He is a member of Konohagakure's Uchiha clan who was believed to have died during the Third Shinobi World War, his only surviving legacy being the Sharingan he entrusted to his teammate, Kakashi Hatake.
Madara is considered a legendary ninja who fought against Hashirama Senju and was considered the "God of Shinobi." After being reanimated, Madara took down the Five Kage, but that was due to having infinite chakra reserves. He was also able to defeat Naruto, Sasuke, and Tobirama during the Fourth Great Ninja War.
Hashirama Senju, aka the First Hokage, was the only one who could ever beat Madara Uchiha in life.
2 Sasuke Uchiha Fought The Strongest With No Fear
Ever since he was a kid, Sasuke Uchiha never feared any challenge. When Naruto was too scared to fight the first foes they met on their first mission, Sasuke showed no sign of fear.
While there's no denying that Itachi is powerful, Madara is simply stronger, whichever way you look at it. With the powers of the 10 Tails and the Six Paths at his disposal, Madara is miles ahead of Itachi, and there's no way the latter can even put up a fight.
Currently, Jigen is the strongest known character in the world of Boruto. His powers were great enough to take on both Naruto Uzumaki and Sasuke Uchiha at the same time. As the fight between the two unraveled, Jigen's superiority over both Naruto and Sasuke became quite apparent.
1) Madara Uchiha
This man was able to tame tailed beasts which really showcased his strength. As a child, Madara was able to awaken his Sharingan with one Tomoe in each eye. His mastery of the Sharingan and jutsu capabilities makes him far stronger than Kakashi.
Obito was not afraid of Itachi. He was only cautious of him. He himself said that “If Itachi knew about him…” but Itachi didn't even know that he wasn't Madara. Obito kept his cards very close to his chest while Itachi involved Obito in Konoha's top confidential matters like Uchiha massacre.
Pain killed Kakashi during his attack on the Hidden Leaf Village, but that was before a lot of training and the addition of the second Mangekyou Sharingan eye. With that enhanced power, Kakashi would be able to slay even the likes of Pain/Nagato.
Madara was much stronger than Obito to begin with, and the fact that his version of the Ten-tails was perfect made him even stronger. When compared to Madara, Obito stands absolutely no chance.
There's no denying that both Itachi and Madara Uchiha are badass characters that the fans can't help but love. When it comes to their charisma as a villain, however, Madara certainly trumps Itachi.
It is revealed later that Sasuke is the sole survivor of the once-powerful Uchiha clan of Konohagakure. He, at the age of seven, survived the massacre of his clan perpetrated by his brother, Itachi, who spared Sasuke's life because he did not consider him worth killing.
Hashirama sought peace for the shinobi world, and to that end founded Konohagakure with his clan, his childhood friend and rival: Madara Uchiha and the Uchiha clan. He would later become the First Hokage (初代火影, Shodai Hokage, literally meaning: First or Founding Fire Shadow) of Konohagakure.