Vecna seeks four victims in total. His first three victims — Chrissy Cunningham, Patrick McKinney, and Fred Benson — are all peers of The Party, people they know from school, which makes Vecna's terror all the more real.
Kind-hearted cheerleader Chrissy Cunningham (Grace Van Dien) is the first character to be cursed by Vecna, and she dies in season 4, episode 1, "Chapter One: The Hellfire Club." After feeling ill, Chrissy sees the clock and begins picturing her mother, who has always been cruel, saying harsh things about her physical ...
While intending to get his revenge on Eleven and Brenner, Vecna also goes after victims who have dealt with traumatizing experiences in the past (reminiscent of his childhood and his time at the Hawkins lab).
Through his "curse" power, Vecna began tormenting and killing various Hawkins residents; with every murder, a new gate would open at the site of the victim's death. Vecna took the lives of Chrissy Cunningham, Fred Benson, Patrick McKinney and Max Mayfield.
School newspaper reporter Fred Benson (Logan Riley Bruner) fled from a deadly car accident that continues to haunt him. Patrick was targeted due to his father's abuse of him. Finally, Vecna targets Max for her trauma from witnessing Billy's death and uses Barb's (Shannon Purser) death as a way to use Nancy.
That's right: Vecna claims his second victim, and it is … Fred Benson, Nancy's right hand at the school paper. Nancy and Fred head over to the trailer park to get the scoop on Chrissy's death, but as soon as they pull in, Fred starts to have the same type of hallucinations Chrissy did.
Clocks represent a passing of time, which can represent the fact that Vecna's victims' time has nearly run out — it is no coincidence that many of the clocks are set to midnight. Throughout the series, we learn that Vecna is a human who found himself trapped in the Upside Down for years thanks to our girl, Eleven.
Hawkins has suffered a lot of trauma over the years - not all of which is connected to Hawkins Lab and the Upside Down - and Vecna's curse takes advantage of that. Vecna appears to carefully choose people who feel a strong sense of guilt or shame, particularly if those emotions are repressed.
His first victim was Chrissy Cunningham. Vecna targeted Chrissy by using her depression and eating disorder against her in his visions. Chrissy was killed in Eddie Munson's trailer, and the first gate was opened on the ceiling.
While caught in Vecna's grip, a tear in the dark dimension reveals her friends on the other side, desperately trying to save her from Vecna's curse. Of course, it's "Running Up That Hill," blasted into Max's headphones that breaks Vecna's hold on her.
In the visions of her trauma induced by Vecna, Chrissy's mother appeared both mentally and emotionally abusive towards her daughter - and it's implied her comments about Chrissy's figure caused her daughter to develop her eating disorder.
Played by Jamie Campbell Bower, each prosthetic was glued to his skin with medical adhesive by prosthetics designer Barrie Gower and his team. For the finishing touch, Vecna was covered in "glossy slime to make him really, really glossy and wet looking," according to Gower.
In episode 7, Vecna is revealed to be Henry Creel (played as a youngster by Raphael Luce), the son of Victor Creel (Robert Englund) and his wife Virginia (Tyner Rushing) shown in the 1950s flashbacks.
Vecna was not always a hideous beast of the Upside Down. He was once a troubled child in the real world named Henry Creel. Henry's “problems” caused his family to move to Hawkins in 1959. However, the exact issues that led to the relocation are unclear.
Once he takes control of the mind, he traumatizes them by showing the visions of their dark past. He takes them to unknown places and gives them a glimpse of himself. The pain of his victims doesn't end here. Every single one of his victims experiences nose bleeding and severe headaches as well.
We know Eleven was born in 1971, which means her mom got pregnant with her during the tests, sometime in 1970. A 1959 flashback in the mid-season 4 finale reveals a 12-year-old One (Jamie Campbell Bower). That puts One, a.k.a. Vecna, as 24 when Eleven was born.
It seems that the reason why Vecna wasn't killing for the seven years after the Hawkins Lab massacre was because he was waiting to become more powerful as the Mind Flayer and Demogorgons took more victims, as he was likely weakened after being thrown into the dimension.
Motivated by a cruel and misanthropic philosophy, Vecna targets particularly traumatized, mentally ill or insecure individuals.
The Hand was a desiccated, mummified left hand. In order to use its powers, the wielder needed to cut off his or her own left hand at the wrist and press the Hand of Vecna against the remainder of the arm.
Vecna doesn't kill Nancy (Natalia Dyer), but he does leave her with a vision: a dark cloud, dead soldiers, and armies of monsters. This is Hawkins' future if Vecna (Jamie Campbell Bower) wins.
Among Vecna's staunchest foes are Kas, Iuz, Saint Cuthbert, the Lady of Pain, Pholtus, and the Circle of Eight. He is also opposed by the Old Faith and the Silent Ones.
Via his 'curse' power, Vecna could make other conscious beings hallucinate and bring them into the mindscape. On March 24, 1986, Max Mayfield entered the mindscape while afflicted with Vecna's curse, but managed to break out of the hallucination and escape to reality.
Though Fred appeared to be bright and level-headed, he harbored extreme guilt for his role in the fatal 1985 car accident, and believed many people look at him as a "murderer." This guilt and mental unrest made him a target of Vecna.