Abstract. Cardiovascular autonomic dysfunction is not uncommon in multiple sclerosis (MS) and is related to the involvement of the vegetative areas of cardiac innervations in the medulla oblongata. It has been suggested that this may contribute to the occurrence of sudden death in MS.
In some cases, it appears that demyelinating lesions, involving brain regions that regulate cardiorespiratory activity, could be considered as the immediate cause of death, but a large proportion appears to be due to other causes such as accidents and trauma.
You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
Disease Course of MS Is Unpredictable
A person with benign MS will have few symptoms or loss of ability after having MS for about 15 years, while most people with MS would be expected to have some degree of disability after that amount of time, particularly if their MS went untreated.
Losing your ability to communicate. Immobility, which may lead to pressure sores and blood clots. Increased levels of pain. Mental decline or confusion.
Average life span of 25 to 35 years after the diagnosis of MS is made are often stated. Some of the most common causes of death in MS patients are secondary complications resulting from immobility, chronic urinary tract infections, compromised swallowing and breathing.
Outlook. The outlook for benign MS isn't clear. Some people who are diagnosed with it never go on to have a more serious disease progression, while others do. Remember, just because you have mild symptoms when you're first diagnosed with MS doesn't mean that they'll stay that way.
There is no cure for multiple sclerosis. Treatment typically focuses on speeding recovery from attacks, reducing new radiographic and clinical relapses, slowing the progression of the disease, and managing MS symptoms. Some people have such mild symptoms that no treatment is necessary.
Over time, more than two-thirds of people remain able to walk, although they may need an ambulation aid such as a cane or walker to do so. Some may choose to use a motorized scooter or wheelchair for long distances, in order to conserve energy and remain more active; others may need to use a wheelchair all the time.
The study found that people with MS lived to be 75.9 years old, on average, compared to 83.4 years old for those without. That 7.5-year difference is similar to what other researchers have found recently.
Does multiple sclerosis shorten your life? Multiple sclerosis itself is not usually lethal, but it can increase the risk of long-term complications, such as infections or trouble swallowing, that can potentially shorten survival. On average, longevity is about five to 10 years shorter in people with MS.
MS itself is rarely fatal, but complications may arise from severe MS, such as chest or bladder infections, or swallowing difficulties. The average life expectancy for people with MS is around 5 to 10 years lower than average, and this gap appears to be getting smaller all the time.
Most scleroderma experts believe that, currently, the most frequent cause of death is pulmonary involvement, either interstitial lung disease or pulmonary arterial hypertension (PAH).
MS can appear at any age but most commonly manifests between the ages of 20 and 40. It affects women two to three times as often as men. Almost one million people in the United States have MS, making it one of the most common causes of neurological disability among young adults in North America.
A person will only receive a diagnosis of benign MS if they have been without severe disabling symptoms of the disease for 15 years. However, this does not mean that a person cannot experience a relapse after this time and see their disease progress into a more severe form.
Healthy adults have a small amount of brain atrophy due to natural ageing, but in many people with untreated MS, brain atrophy occurs at a much faster rate. Current MS treatments aim to prevent new central nervous system lesions forming that lead to irreversible damage and brain atrophy.
Late-onset MS shows similar nervous system changes as early onset MS. But when you develop the condition later in life, it may progress faster.
Multiple sclerosis (MS) is not generally considered life-threatening and most people will live a normal life-span. One study has found that the average life expectancy for people with MS is 76 years of age.
MS is a lifelong disease. Your symptoms may gradually get worse as it progresses and parts of the brain and spinal cord get damaged. But a few simple lifestyle changes can help you stay mobile and have a good quality of life for a long time.
Constant fatigue is common for people with MS. This tiredness can impact all aspects of life, including effective brain use and the ability to go out and partake in activities. The symptoms of MS can cause constant discomfort and disability that limit a person's ability to go about daily activities.