Use of vitamin E can interact with many conditions. For example, research suggests that oral use of vitamin E might increase the risk of prostate cancer. Other research suggests that vitamin E use might increase the risk of death in people with a severe history of heart disease, such as heart attack or stroke.
People with a history of heart disease should avoid taking doses of vitamin E greater than 400 IU daily. Diabetes: Vitamin E might increase the risk for heart failure in people with diabetes. People with diabetes should avoid taking doses of vitamin E greater than 400 IU daily.
In supplement form, however, high doses of vitamin E might increase the risk of bleeding (by reducing the blood's ability to form clots after a cut or injury) and of serious bleeding in the brain (known as hemorrhagic stroke).
In addition, an analysis of clinical trials found patients who took either synthetic vitamin E or natural vitamin E in doses of 400 IU per day -- or higher -- had an increased risk of dying from all causes, which seems to increase even more at higher doses.
Currently, the recommended daily amount of vitamin E daily is 15 milligrams. You can get this from three ounces of almonds. Since vitamin E is a fat soluble vitamin, if you have problems absorbing fat, you may need more of it in your diet and should consider a supplement.
Thus, newborns, particularly premature newborns, are at increased risk of vitamin E deficiency. However, with age, risk decreases because infants usually get enough vitamin E in breast milk or in commercial formulas. Adults can store large amounts of vitamin E in fat tissue, making the deficiency less likely.
Vitamins D, E and K
“Studies have shown that a person's absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together,” says Dr. Chris Airey, M.D. “It's advised that you take these vitamins at least 2 hours apart to maximize your absorption.”
Vitamin E is an essential nutrient for the body. It helps in metabolism and reduces oxidative stress. However, excess vitamin E can act as a blood thinner. It can cause fatal bleeding and interfere with other blood-thinning medications such as aspirin and warfarin.
The Food and Nutrition Board of the Institute of Medicine has set an upper tolerable intake level (UL) for vitamin E at 1,000 mg (1,500 IU) per day for supplemental vitamin E. Based on clinical trials, the dose often used for disease prevention and treatment for adults is 400 to 800 IU per day.
Numerous studies have reported that vitamin E exhibits anti-proliferative, anti-survival, pro-apoptotic, and anti-angiogenic effects in cancer, as well as anti-inflammatory activities. There are various reports on the benefits of vitamin E on health in general.
Vitamin E supplementation diet counteracts the molecular substrates underlying synaptic plasticity and cognitive function in the hippocampus. Vitamin E dietary supplementation can protect the brain against the effects of mild TBI on synaptic plasticity and cognition. Declines rate of cognitive impairment.
In the absence of deficiency, supplementation may actually prove harmful to hair. Over-supplementation of certain nutrients, including selenium, Vitamin A, and Vitamin E, has actually been linked to hair loss [4,8–11].
Among main risk factors are high blood pressure, high blood levels of LDL (bad cholesterol) and triglycerides. Studies found that vitamin E supplementation can help lower systolic blood pressure (the top number) without affecting the diastolic blood pressure (bottom number) (2).
The forms of α-tocopherol that meet the recommended intakes are RRR-α-tocopherol — the only naturally occurring form of vitamin E — and the three synthetic isomers, RRS-, RSR-, and RSS-α-tocopherol, which are found in nutritional supplements and fortified food.
Which vitamins do I need to avoid if I have kidney disease? You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K. These vitamins are more likely to build up in your body and can cause harm if you have too much.
Vitamin E - inhibits pre-fat cells from changing into mature fat cells, thus reducing body fat. Vitamin D - deficiency strongly linked to poor metabolism of carbohydrates; Genes that are regulated by vitamin D may alter the way fat cells form in some people.
Foods rich in vitamin E are known to lower the risk of heart disease because of its blood thinning properties. Vitamin E rich foods decrease the risk of blood -platelet clumping which could lead to clot formation.
Researchers conducted angiography on the subjects after 2 years of intervention and found that supplementation of >100 IU/day of vitamin E caused the least progression in coronary artery lesions due to a lower rate of stenosis [28].
Certain medications (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat) can decrease the absorption of vitamin D. Take your doses of these medications as far as possible from your doses of vitamin D (at least 2 hours apart, longer if possible).
Taking too much vitamin E may increase your risk of side effects. High doses of vitamin E (400 units or more per day) may increase the chance of rare but very serious side effects. There is no proof that high doses of vitamin E help to prevent or treat heart disease.
Half an avocado also contains up to 20% of your vitamin E requirement. Mangos and kiwis also have vitamin E, but they have slightly less vitamin E content than avocados. All three fruits are great options, however, especially for people with nut allergies or sensitivities.
Vitamin E has been shown to increase oxidative resistance in vitro and prevent atherosclerotic plaque formation in mouse models. Consumption of foods rich in vitamin E has been associated with lower risk of coronary heart disease in middle-aged to older men and women.