Olanzapine may be used alone or with other medications to treat mental health conditions. It is also FDA approved for the following indications: Acute treatment of manic or mixed episodes of bipolar disorder. Maintenance (long-term) treatment of bipolar disorder.
Olanzapine is used to treat schizophrenia. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness).
Olanzapine helps to manage symptoms of mental health conditions such as: seeing, hearing, feeling or believing things that others do not, feeling unusually suspicious or having muddled thoughts (schizophrenia) feeling agitated or hyperactive, very excited, elated, or impulsive (mania symptoms of bipolar disorder)
What happens if a normal person takes olanzapine? Olanzapine is prescribed for people who have chronic schizophrenia and bipolar disorder. In ordinary people, intake of olanzapine increases weight by at least 2–3 kgs over six weeks. Other side effects include dry mouth, tremors, restlessness, and muscle contractions.
Olanzapine (Zyprexa) is considered a mood stabilizer, along with lithium (Lithotabs), certain anticonvulsants (anti-seizure medications), and some other antipsychotics. Olanzapine (Zyprexa) can also help to treat depression when combined with fluoxetine (Prozac).
It has a profoundly calming effect in many people. It can stop “racing thoughts” that can be one of the most severe symptoms of bipolar disorder, especially in Bipolar II — as well as the more obvious symptoms of paranoia or delusions as seen in Bipolar I.
In functional studies, olanzapine was a potent antagonist at 5HT and D2 receptors, suggesting it might be useful as an antipsychotic agent.
Alcohol can increase the nervous system side effects of OLANZapine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with OLANZapine.
Atypical antipsychotics such as quetiapine, aripiprazole, olanzapine, and risperidone have been shown to be helpful in addressing a range of anxiety and depressive symptoms in individuals with schizophrenia and schizoaffective disorders, and have since been used in the treatment of a range of mood and anxiety disorders ...
Olanzapine demonstrated a modest effect in the treatment of bipolar depression with a substantially enhanced effect in combination with fluoxetine. Maintenance trials showed olanzapine to be more efficacious than placebo in the prevention of manic and depressive relapses and non-inferior to lithium or valproate.
Providers often use second-generation antipsychotic medications such as risperidone (Risperdal) or olanzapine (Zyprexa) to treat hyperactivity, aggression, and disruptive conduct in children and young adults with ADHD or DICDs.
Olanzapine is an atypical antipsychotic used to treat bipolar disorder, schizophrenia and psychosis.
Antipsychotic drugs don't cure psychosis but they can help to reduce and control many psychotic symptoms, including: delusions and hallucinations, such as paranoia and hearing voices. anxiety and serious agitation, for example from feeling threatened. incoherent speech and muddled thinking.
Olanzapine binds loosely to the receptor and dissociates easily, allowing for normal dopamine neurotransmission. The effect on the D2 receptors leads to a decrease in positive symptoms in patients, including hallucinations, delusions, and disorganized speech, thought, and behavior.
Olanzapine is potentially effective and safe in panic disorder.
What are the potential long-term effects of taking Zyprexa? Your doctor should monitor for progression of potential long-term side effect of Zyprexa, which can include weight gain, high blood sugar, tardive dyskinesia, and high-fat levels in the blood.
Olanzapine is considered moderately toxic in overdose, more toxic than quetiapine, aripiprazole, and the SSRIs, and less toxic than the monoamine oxidase inhibitors and tricyclic antidepressants.
Olanzapine and Weight Gain
Amongst those prescribed olanzapine early in psychosis management, 80% experience an increase of ≥7% of their baseline body weight (10, 11).
Second-generation antipsychotics, such as quetiapine and olanzapine, are often abuse for their sedative and anxiolytic effects.
Predominantly sedating are olanzapine, quetiapine immediate and extended release, ziprasidone, asenapine, and iloperidone. Agents that are neither activating nor sedating are paliperidone and brexpiprazole.
User Reviews for Olanzapine to treat Agitation. Olanzapine has an average rating of 7.7 out of 10 from a total of 35 ratings for the treatment of Agitation. 77% of reviewers reported a positive experience, while 14% reported a negative experience.
Antipsychotic medications are typically used to treat psychosis, a condition that involves some loss of contact with reality. People experiencing a psychotic episode often experience delusions (false beliefs) or hallucinations (hearing or seeing things others do not see or hear).
Formerly known as major tranquilizers and neuroleptics, antipsychotic medications are the main class of drugs used to treat people with schizophrenia. They are also used to treat people with psychosis that occurs in bipolar disorder, depression and Alzheimer's disease.
They can cause movement disorders such as twitching and restlessness, sedation and weight gain, and lead to diabetes. Because of these side effects, antipsychotic drugs are usually only used to treat severe mental illnesses such as schizophrenia or bipolar disorder.