Vitiligo sometimes runs in families, but the inheritance pattern is complex because multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected.
Others think it is a genetic condition, as affected kids often have a family member who also has it. What is known is that the risk of developing vitiligo increases in kids with a family or personal history of thyroid disease, diabetes, and certain conditions like alopecia (an autoimmune disease that causes hair loss).
What causes vitiligo? Vitiligo is an autoimmune disease. This type of disease develops when your immune system attacks part of your own body. If you have vitiligo, your immune system attacks cells in your body called melanocytes. These are cells that make pigment.
Vitiligo can start at any age, but usually appears before age 30. Depending on the type of vitiligo you have, it may affect: Nearly all skin surfaces. With this type, called universal vitiligo, the discoloration affects nearly all skin surfaces.
Vitiligo often starts as a pale patch of skin that gradually turns completely white. The centre of a patch may be white, with paler skin around it. If there are blood vessels under the skin, the patch may be slightly pink, rather than white. The edges of the patch may be smooth or irregular.
People can develop vitiligo at any age, but approximately one-half of cases are diagnosed either in childhood or before someone turns 20. The first signs of vitiligo are white patches on the skin, which can develop anywhere on the body, including on the face, arms, hands, genitals, and buttocks.
Stress increases the levels of catecholamines, neuropeptides, and cortisol that are higher in vitiligo patients [37–39] suggesting their role in the pathogenesis of vitiligo.
Inheritance. Vitiligo sometimes runs in families, but the inheritance pattern is complex because multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected.
If a person has vitiligo, the risk that a first-degree family member (parent, child, or sibling) is 5%, or 5 times higher than the general population.
Pityriasis versicolor can sometimes be confused with vitiligo, as they both cause the skin to become discoloured in patches. But there are ways to tell the difference: vitiligo often develops symmetrically (on both sides of your body at the same time), while pityriasis versicolor may not.
However, it is not a rule that children of vitiligo parents will always have vitiligo. Relatively, the chance of the offspring having vitiligo may be somewhat higher if one or more of the parents have vitiligo. Vitiligo does not spread by touch or contact. It does not affect marriage life or physical relationship.
It affects 0.5–2% of the population worldwide regardless of race and gender [4, 5]. Women and men are equally affected by the vitiligo [6]. Although it can initiate at any time [7, 8], the initiation in 50% of the people is before 20 years [9].
After 6 to 12 months, segmental vitiligo tends to stabilize, meaning that the color loss stops. Once it stops, most people with segmental vitiligo don't develop new patches or spots.
Vitiligo (pronounced: vittle-EYE-go) is a skin disorder that causes depigmentation (loss of skin color) in irregular patchy patterns. The disorder itself is rare, affecting only about 0.5% to 1% of the world's population.
Hypopigmented spots that are NOT vitiligo. If the spots are not truly white, but hypopigmented and not depigmented (they don't enhance by Wood's lamp), then they are NOT vitiligo and could be any number of different diseases and conditions.
To the best of our knowledge, vitamin D significantly affects melanocytes and keratinocytes. Studies suggest that vitamin D3 increases tyrosinase activity and melanogenesis in vitro [12], which may lead to repigmentation in vitiligo skin lesions.
Moreover, people with vitiligo lack melanin, which is the body's natural protection from the sun, so sun exposure can be particularly dangerous. That's why it's vital that people with vitiligo use broad-spectrum sun protection with an SPF (sun protection factor) of 30 and above.
Research suggests that most people who develop vitiligo do so during childhood. As you age, Dr. Mohta says untreated vitiligo often progresses to involve the surrounding skin or create new patches of discoloration.
Localized: Skin patches are found on limited areas of the body. Generalized: Skin patches are scattered around the body. Mucosal : Vitiligo affects the mucous membranes found in the mouth and/or genitals. Focal: Skin patches remain in a small area of the body without spreading in the first two years.
Say Hello to Sunshine: Expose the affected areas to early morning sunlight i.e. just as soon as the sun rises as it consists of ultraviolet A-rays (320-400nm) which stimulate pigment-forming cells (melanin).