Exposure to sunlight, even for short periods of time, may cause skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine: Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
There are no standard routine tests to monitor the use of doxycycline. The most significant side effect is hepatic injury, which can be avoided by administering doxycycline hyclate at the recommended dosage and keeping contraindications and adverse effects in mind.
Examination and Evaluation
Monitor signs of hypersensitivity reactions or anaphylaxis, including pulmonary symptoms (tightness in the throat and chest, wheezing, cough dyspnea) or skin reactions (rash, angioedema, pruritus, urticaria).
Do not take your medicine together with dairy products. This is because dairy foods like milk, cheese and yoghurt can stop your body from absorbing doxycycline. You can have dairy products a few hours before or after your dose. It's best not to drink alcohol with doxycycline because it can stop it working properly.
Doxycycline use in children <8 years is now considered acceptable in courses up to 21 days. As a theoretical precaution, avoid prolonged (>21 days) or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).
Doxycycline impairs cardiac mitochondrial bioenergetic function, and results in diastolic dysfunction, which was exacerbated in diabetic animals.
Some possible uncommon but serious side effects of doxycycline include: a life-threatening allergic reaction (symptoms are trouble breathing; closing of the throat; swelling of the lips, tongue, or face; hives)
High blood pressure in the brain: Doxycycline may increase the risk of high blood pressure in the brain. Contact your doctor right away if you experience blurred vision, double vision, and headache.
Try to avoid lying down for at least 30 minutes after taking doxycycline. This helps to prevent any irritation. If you're taking doxycycline for malaria, start your treatment 1 or 2 days before going to an area with malaria. Stop taking it 4 weeks after leaving the area.
You should take this medicine on an empty stomach, preferably at least 1 hour before or 2 hours after meals. You should take this medicine with a full glass of water while sitting or standing. To prevent throat irritation, do not lay down right after taking this medicine.
Do not take Doxycycline immediately before going to bed. While you are lying down the pill can reflux back up into the esophagus, where it can irritate or even ulcerate the lining of the esophagus.
An AMI occurred as the first event in 3,622 patients receiving clarithromycin, 2,408 receiving doxycycline, and 6,321 receiving erythromycin, and a stroke occurred as the first event in 3,807 patients receiving clarithromycin, 2,480 receiving doxycycline, and 6,732 receiving erythromycin (Web Table 5).
Feeling a rapid heartbeat (palpitations), feeling dizzy, or fainting.
Serious side effects
bruising or bleeding you cannot explain (including nosebleeds), a sore throat, high temperature and feeling tired or generally unwell – these can be signs of blood problems.
Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach - PMC. The .
Doxycycline is reported to cause acute liver failure, hepatocellular necrosis, and cholestasis. Cefuroxime is a second generation cephalosporin that has also been reported to cause cholestasis, ischemic hepatitis, and liver failure.
Doxycycline is used to treat bacterial infections in many different parts of the body. It is also used to treat pimples and abscesses (usually on the face) that are caused by rosacea, also known as acne rosacea or adult acne.
If you feel nauseous
The drugs can be quite harsh on the stomach, and might make you feel sick, or give you a dodgy tummy. This feeling normally passes within a few days, as your body adjusts.
Moreover, doxycycline was found to possess an anti-inflammatory, antioxidant and anti-MMP role in COPD19. The findings of the present study also suggest that the improvement in lung function and quality of life in COPD patients can be attributed to the above-mentioned effects of doxycycline.
The symptoms of doxycycline-induced oesophagitis include sudden onset of pain on swallowing and often very severe chest pain. A temporal relationship between onset of symptoms and ingestion of doxycycline should be considered as part of the diagnosis.
Nurses are responsible for recognizing patients' symptoms, taking measures within their scope of practice to administer medications, providing other measures for symptom alleviation, and collaborating with other professionals to optimize patients' comfort and families' understanding and adaptation.
WHAT ARE THE THREE CHECKS? Checking the: – Name of the person; – Strength and dosage; and – Frequency against the: Medical order; • MAR; AND • Medication container.
Registered Nurse Job Duties and Responsibilities
Assessing, observing, and speaking to patients. Recording details and symptoms of patient medical history and current health. Preparing patients for exams and treatment. Administering medications and treatments, then monitoring patients for side effects and reactions.
Conclusions: Doxycycline can enhance the anticoagulant effect of warfarin. This is likely due to competitive interaction for albumin binding and possibly inhibition of the cytochrome P-450 system. An increase in plasma levels of free warfarin may result in severe bleeding.