Some studies have shown an association between antibiotic use and subsequent depression. For example, a nested case-control study reported that antibiotic treatment was associated with a high risk of depression (adjusted OR: 1.23 [95% CI: 1.18–1.29] for penicillins and 1.25 [95% CI: 1.15–1.35] for quinolones) [23].
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably depression and anxiety.
Conclusion: Recurrent antibiotic exposure is associated with increased risk for depression and anxiety but not for psychosis.
Previous studies have found that even one course of antibiotics can increase the risk of depression and anxiety. Steenbergen adds: 'As well as the disruption to the microbiome caused by antibiotics, we also know that inflammation from an infection can itself affect the brain.
Stomach discomfort or nausea is a common side effect of amoxicillin. Less common symptoms include abdominal pain and vomiting. Taking your dose of amoxicillin with a meal may help prevent this side effect. To cope with an upset stomach, eat bland, easy-to-digest foods like soups, crackers, and toast.
Amoxicillin is a penicillin-based, broad-spectrum antibiotic (Box). Its potential psychiatric side effects include encephalopathy, irritability, sedation, anxiety, and hallucinations. These symptoms usually are managed by reducing the dosage or discontinuing the medication.
Antibiotics can lead to disruption in brain function, that causes mental confusion accompanied by hallucinations and agitation.
A five-day course of some broad-spectrum antibiotics can wipe out as much as one-third of your gut bacteria,” explains nutritionist Suchita Mukerji. Any disturbance in the gut shows up as acidity, discomfort and bloating, and makes the body susceptible to fatigue, brain fog and further infections.
New research indicates that antibiotics used to treat patients with infections could be linked to a disruption in brain function, called delirium, and to other brain problems. Delirium causes temporary confusion that may be accompanied by hallucinations and agitation.
As shown in Table 1, compared to minocycline, 15 of the 23 antibiotics were associated with a significantly increased odds of psychosis (OR = 1.67–9.48), including amoxicillin/clavulanate, ceftriaxone, SMX/TMP, cephalexin, azithromycin, doxycycline, nitrofurantoin, erythromycin, cefuroxime, amoxicillin, cefepime, ...
Interactions between your drugs
No interactions were found between amoxicillin and sertraline. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
But despite their ability to treat potentially dangerous infections, many people can experience uncomfortable side effects when taking antibiotics, including bloating, indigestion, nausea, and vomiting. Though less common, some antibiotics can also make you feel tired or weak.
So, no, taking an antibiotic doesn't cause anxiety or panic attacks. Taking an antibiotic, however, can cause anxiety-like symptoms as well as aggravate existing anxiety symptoms, including increasing a sense of nervousness, agitation, danger, and foreboding.
Antibiotics, like amoxicillin, may cause an upset stomach, so taking it with a meal or a snack can help prevent certain stomach-related side effects. These can include nausea, vomiting, or diarrhea. It can be tough to remember to take all of your doses as is, let alone remembering to combine your doses with food.
Four fluoroquinolone antibiotics, which were ofloxacin, levofloxacin, moxifloxacin, and ciprofloxacin, were all reported to be associated with delirium [16–19].
Dizziness and a dry mouth are both possible side effects of many antibiotics, so this could be the reason for these symptoms, but they are also signs of dehydration, so make sure you're getting enough to drink.
Typically, it will take the body time to balance the microbiome to healthy, diverse bacteria levels. In fact, research shows that it takes about 6 months to recover from the damage done by antibiotics. And even then, the body might not even be back to its pre-antibiotic state.
After an antibiotic course, recovery of the gut microbiome can take some time. In general, after short-term antibiotic use (between five and ten days), studies have observed it can take at least one to two months for most bacterial groups to recover to pre-antibiotic levels2,3,13–16.
Stopping antibiotics when symptoms have substantially resolved appears to be effective and safe for many patients, especially those who are unlikely to have a bacterial infection or who have a self-limiting bacterial infection.
Research indicates that hormone levels in women using combined oral contraceptives are not lowered by the use of ampicillin, amoxicillin, clarithromycin, metronidazole, quinolones (ciprofloxacin, ofloxacin), doxycycline, tetracycline, or fluconazole.
Conclusions: Antibiotic treatment can be associated with (hypo)mania.
How long will it take for side effects from amoxicillin to go away? The side effects of amoxicillin will resolve when you are done taking the medication. Your body clears the medication quickly, typically within 8-12 hours of your last dose.
Generally, yes. Antibiotics are incredibly efficient at helping fight off diseases. Like any medication or medical procedure, taking risks and benefits are associated with taking them. While fatigue, drowsiness and sleepiness aren't widespread effects of antibiotics, some can cause more severe side effects.