The most prevalent symptoms of vitamin B12 deficiency are neurologic, such as paresthesia in hands and feet, muscle cramps, dizziness, cognitive disturbances, ataxia, and erectile dysfunction, as well as fatigue, psychiatric symptoms like depression, and macrocytic anemia.
In addition, B12 helps metabolize protein and fat, which are both essential for building muscle. Therefore, without enough B12, your muscles become weak and you end up feeling anemic and drained. This nutrient is also responsible for the production of white blood cells, the cells that support the immune system.
“Our findings demonstrate that low B12 levels are associated with greater walking and balance problems, possibly due to the known effect of B12 deficiency on the central and peripheral nervous systems,” said Christine.
Over time, peripheral nerve damage resulting from vitamin B-12 deficiency can lead to movement problems. Numbness in the feet and limbs may make it hard for a person to walk without support. They may also experience muscle weakness and diminished reflexes.
Key points about vitamin B12 deficiency anemia
Without enough red blood cells, your tissues and organs don't get enough oxygen. Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.
A deficiency in magnesium is most likely to cause muscle stiffness because this nutrient is needed to keep muscles flexible and moving efficiently, as well as relaxed.
People with vitamin B12 deficiency can have neurological symptoms and/or damage without anemia (lack of red blood cells). General physical symptoms of vitamin B12 deficiency can include: Feeling very tired or weak. Experiencing nausea, vomiting or diarrhea.
Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment. If you can, it's a good idea to address what's causing the deficiency.
Stage 1 is decreased levels of vitamin B12 in the blood. Stage 2 is low concentration of vitamin B12 in the cell and metabolic abnormalities. Stage 3 is increased levels of homocysteine and MMA and decreased DNA synthesis resulting in neuropsychiatric symptoms. Stage 4 is macrocytic anemia.
Vitamin B12deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet.
Deficiency of vitamin B12 causes hyperhomocysteinemia (HHcy) [5,16], and elevated homocysteine is known to lead to an inflammatory state, a risk factor for coronary heart disease [16] and insulin resistance [17,18].
There are certain foods that also need a cut-down in case of vitamin B12 deficiency. “Some foods and drinks can interfere with vitamin B complex intake like alcohol, caffeine and processed foods, etc should be avoided completely,” Shah added.
A lack of B12 may lead to depression, confusion, memory problems, and dementia. It also can affect your balance. B12 supplements are usually safe.
Since your body doesn't make vitamin B12, you have to get it from the foods you eat or from supplements. You can get vitamin B12 deficiency if you can't absorb vitamin B12 due to problems with your gut or if you have pernicious anemia, which makes it difficult to absorb vitamin B12 from your intestines.
Common causes of vitamin B12 deficiency include inadequate dietary amounts (eg, in vegans), impaired absorption, age-related decreased acid secretion, and autoimmune metaplastic atrophic gastritis (which causes pernicious anemia).
Muscle stiffness often arises after changing exercise routines, overusing muscles, or being physically inactive for long periods of time. Otherwise, muscle stiffness can be caused by an underlying condition, including myopathy, neuromuscular disorders, and neurologic disorders.
There may be several reasons why your muscles are always tight. The most common reasons are dehydration, poor sleeping positions, muscle weakness, and muscle inhibition.
A severe vitamin B12 deficiency may damage nerves, causing tingling or loss of sensation in the hands and feet, muscle weakness, loss of reflexes, difficulty walking, confusion, and dementia. The diagnosis of vitamin B12 deficiency is based on blood tests.
Muscle cramps and weakness
If a B12 deficiency is preventing the body from producing enough red blood cells to get oxygen to muscle tissues, you may experience associated symptoms, like sporadic muscle cramps or weakness [3].
Pernicious anemia is a relatively rare autoimmune disorder that causes diminishment in dietary vitamin B12 (cobalamin) absorption, resulting in B12 deficiency and subsequent megaloblastic anemia. It affects people of all ages worldwide, particularly those over 60.
If you have a vitamin B12 deficiency, it can take months—even a year—to correct it. Vitamin B12 deficiency is common, especially among vegetarians and older adults. Also known as cobalamin , it is a water-soluble vitamin found in meat, fish, and dairy. Vitamin B12 is essential for brain and nerve function.
Vitamin B12 is most beneficial for circulation as it helps to keep nerve and blood cells working well. Without enough vitamin B12, the body may not be able to create enough red blood cells to transport oxygen around the body.