Currently, Ozempic is only approved for use in people with type 2 diabetes. However, doctors may prescribe Ozempic off-label for weight loss. For this purpose, they may prescribe the drug to someone who does not have type 2 diabetes.
Even in non-diabetics, Ozempic can increase the risk of low blood sugar due its effects on insulin secretion and glucagon inhibition. Symptoms like confusion, rapid heartbeat, sweating and hunger may occur in severe cases.
While the Therapeutic Goods Administration (TGA) has approved Ozempic for diabetes management, it has not yet been approved for weight management. Still, the benefits of this medication are well known in the medical community, and your doctor can help you determine if it is right for you.
It's also approved for use in people with a BMI of 27 or greater, who have an accompanying overweight- or obesity-related condition, such as high blood pressure or sleep apnea,” Dr. Dominguez says. Ozempic is sometimes prescribed off-label for weight loss but is mostly used to treat people with diabetes, she says.
After meeting with the TGA, Novo Nordisk, pharmaceutical wholesalers and other organisations representing health professionals and patient groups in late June, the RACGP has recommended that prescriptions for Ozempic should continue to be limited to patients who satisfy the TGA-approved indications of type 2 diabetes ...
Medicare covers Ozempic for Type 2 diabetes
Medicare prescription drug plans might cover Ozempic, but only to treat diabetes. In 2021, Medicare spent over $2.6 billion to cover Ozempic prescriptions. Because it's an outpatient prescription drug, Ozempic falls under Medicare Part D.
If you have private or commercial insurance, such as insurance you receive through an employer, you may be eligible to pay as little as $25 for a 1-, 2-, or 3-month prescription (maximum savings of $150 per 1-month prescription, $300 per 2-month prescription, or $450 per 3-month prescription).
Ozempic isn't approved for weight loss. But because of how it works, some people taking Ozempic lose weight as a side effect. If you don't have diabetes, taking Ozempic for weight loss is considered an off-label use. Wegovy, a higher-dose version of Ozempic, is approved to help people manage their weight.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
A study found that at the highest dose of Wegovy (2.4 mg), patients lost on average 15% of their total body weight after 1 year. In patients with diabetes, one study showed that taking Ozempic at the highest dose of 2 mg led to on average ~15 lbs (6.9 kg) weight loss after 40 weeks.
However, Ozempic isn't appropriate for everyone. According to Dr. Singh, people who are not candidates for Ozempic include people with: A personal history of pancreatitis (inflammation of the pancreas)
On the PBS, Ozempic costs Australians about $42 a month (four weekly injections). On a private prescription, the cost is about $132 a month. According to the medical news website WebMD, Ozempic can cost uninsured Americans more than a $US1000 a month and many flock to Canada to save $US700 a month.
Providers (doctors, nurse practitioners and physician assistants) can prescribe either Ozempic ("off label") or Wegovy for weight loss, but insurance companies will usually only cover these medications for their FDA-approved uses (Ozempic for only diabetes and Wegovy for only medical obesity treatment).
Medicare prescription drug plans might cover Ozempic, but only to treat diabetes. In 2021, Medicare spent over $2.6 billion to cover Ozempic prescriptions. Because it's an outpatient prescription drug, Ozempic falls under Medicare Part D. Original Medicare (Part A and/or Part B) won't cover it.
Ozempic has been in short supply since April 2022 because it's being prescribed for the off-label treatment of obesity. Picture: Getty Images / Mario Tama. The TGA is recommending those using Ozempic for other conditions to consult with their doctor to have their treatment reassessed.
The availability of Ozempic (semaglutide) in Australia continues to improve and the supplier, Novo Nordisk, anticipates steady ongoing supply.
Ozempic was developed to help people with type 2 diabetes manage their blood sugar levels but it can also lead to significant weight loss of 15 to 20 per cent of body weight in some people.
Discuss your goals: Talk to your doctor about your diabetes management goals and how Ozempic may help you achieve them. Whether it's better blood sugar control or weight loss, make sure your doctor understands what you're aiming for.
The most common side effects of Ozempic, according to the drug's website, are nausea, stomach pain, constipation, diarrhea and vomiting. Novo Nordisk, the maker of Ozempic and Wegovy, told CBS News that the drugs "are a well-established class of medicines, which have demonstrated long-term safety in clinical trials.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.