Taking glucosamine sulfate and acetaminophen together might reduce the effectiveness of both the supplement and medication. Warfarin (Jantoven). Taking glucosamine alone or in combination with the supplement chondroitin might increase the effects of the anticoagulant warfarin. This can increase your risk of bleeding.
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Most commonly it is taken alongside magnesium supplements as a joint vitamin to treat disorders such as arthritis.
Large doses of minerals can compete with each other to be absorbed. Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.
Magnesium and calcium/multivitamin
Additionally, she says to refrain from taking calcium, magnesium or zinc together as they will “compete for absorption.”
The best time to take your glucosamine supplement is… the same time each day, no matter what time that is. With most glucosamine supplements, it is suggested by some experts that you take it with your meals to support digestive health.
With Vitamin C for a Synergistic Effect
Glucosamine Sulphate 1500mg with Vitamin C represents the perfect daily support for the maintenance of healthy cartilage function, as confirmed by the European Food Safety Authority.
Glucosamine and chondroitin are two of the most commonly used supplements for arthritis. They're components of cartilage—the substance that cushions the joints. Research on these supplements has been mixed, in part because studies have used varying designs and supplement types.
Combining multiple supplements or taking higher-than-recommended doses can increase the risk that they can cause harm, said Kitchin. "You really can't get toxic doses of nutrients through food, but you can absolutely get toxic doses through supplements," Kitchin said.
Glucosamine may affect blood sugar and insulin levels. However, studies are mixed. Talk to your doctor before taking this supplement if you have diabetes or insulin resistance. Animal studies show that glucosamine may further increase LDL "bad" cholesterol levels if you eat a lot of fatty foods.
Warfarin (Coumadin) interacts with GLUCOSAMINE
This can increase the risk for serious bruising and bleeding. Don't take glucosamine if you are taking warfarin.
It is OK to take glucosamine every day, but check with your healthcare provider. For example, with osteoarthritis, the following doses have been studied: By mouth: 1,500 milligrams (mg) per day, taken either at once, in two doses of 750 mg, or in three doses of 500 mg.
Interactions between your drugs
No interactions were found between ascorbic acid / chondroitin / glucosamine / manganese sulfate and Calcium, Magnesium and Zinc. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Vitamin C is effectively an acid (it's sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.
Glucosamine and chondroitin are supplements that may address joint pain and inflammation caused by arthritis and osteoarthritis. They may cause insomnia as well as headaches that lead to further sleeplessness.
Reported improvement (e.g. reduction in painful symptoms) varies from three weeks to as much as eight weeks. Some studies have shown continued improvement of symptoms after oral intake was stopped. Generally, if there is no pain reduction after two months, there is little chance of improvement.
Glucosamine and chondroitin protect cells called chondrocytes, which help maintain cartilage structure. In theory, these supplements have the potential to slow cartilage deterioration in the joints, and to reduce pain in the process.
Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin). Magnesium should be taken 1 hour before or 2 hours after taking these medications. Quinolone and tetracycline antibiotics include: Ciprofloxacin (Cipro)
Therefore, conditions that affect the gut and digestion, like celiac disease, chronic pancreatitis, Crohn's disease, and cystic fibrosis, can reduce vitamin D absorption.