Compared to unaffected controls, women with PCOS had a significantly increased risk of developing bipolar disorder after adjusting for age, medical comorbidity, and different treatment options (1.05 vs. 0.12 per 1,000 person-years, HR: 8.29, 95% CI: 4.65–14.7).
People who have been diagnosed with PCOS are about 3 times more likely to be diagnosed with anxiety and depression than people without PCOS (1-3). People with PCOS are also much more likely to report symptoms of anxiety and depression and those symptoms are more likely to be severe (3-5).
In a study on psychological disorders in women with PCOS, higher risks for depression disorder (2.79% higher), anxiety disorder (2.75% higher), bipolar disorder (1.78% higher), and major depression disorder (1.37% higher) were reported for women with this syndrome than the general population.
Mood swings: Because of the hormonal imbalance, women with PCOS also have a higher risk for depression, anxiety and extreme or rapid changes in mood. Heavy, painful periods: PCOS can cause painful periods with heavy bleeding. This can cause additional issues, such as anemia, and is often unpleasant and even scary.
Valproate is an anticonvulsant, one of several used to treat bipolar disorder as a mood stabilizer. It is also used to treat epilepsy. One study showed that 43% of the women receiving valproate for epilepsy had polycystic ovaries. Thats more than four times the average rate.
PCOS has a number of effects on the body which impact mental health and many ladies with PCOS suffer with mood swings.
Women with PCOS often report signs of mood swings, depression and anxiety. Mood swings can feel like rapidly fluctuating emotions that can manifest as irritability, temper, sadness and/or anxiety that results from hormonal imbalance. Many women do experience signs of mood swings, especially near their menstrual cycle.
Some women have adrenal-dominant PCOS while other women have ovary-dominant PCOS, and many women have a combination of both. Women with PCOS have also been found to produce more cortisol at baseline than women without PCOS. This means that women with PCOS may have more sensitive stress response systems.
These commonalities as well as anecdotal clinical observations have sparked a small, growing body of new research that points to an increased risk of comorbidity between the severe psychiatric disorder of BPD and the physical, endocrinological disorder of PCOS.
Previous studies have found that women with polycystic ovary syndrome (PCOS) have some degree of brain function change as well as cognitive function and emotions, such as poor executive functioning and memory, anxiety and depressive symptoms.
Conclusions: Child maltreatment is independently associated with PCOS in women without psychiatric disorders. In the context of all maltreatment subtypes, emotional abuse remained associated with PCOS, suggesting its unique effect on this endocrinopathy.
There is also a long list of symptoms and disorders that are linked to PCOS such as insulin resistance, weight gain, depression, anxiety, eating disorders, body image issues, pregnancy-related complications, nonalcoholic fatty liver disease, endometrial cancer, infertility, and many more.
When you take too much stress or overthink your PCOS, your body releases the stress hormone known as cortisol. In addition, women with PCOS are worried about obesity, irregular period cycle, hormone fluctuations, male pattern balding, and excess facial and body hair.
PCOS is associated with a higher prevalence of type 2 diabetes, cardiovascular disease, and endometrial cancer. The association between psychiatric disorders and PCOS is well known. The incidence of depression, anxiety, and personality and eating disorders in the PCOS group is higher than in the general population.
However, their PCOS hormonal imbalance does not change with age, so they may continue to have symptoms of PCOS. Also, the risks of PCOS-related health problems, such as diabetes, stroke, and heart attack, increase with age. These risks may be higher in women with PCOS than those without.
Women with PCOS are known to have a higher risk of developing depression and adult ADHD. This risk, in turn, might cause an increase in psychiatric morbidity in their children [18].
A “bipolar meltdown” is, much like “bipolar anger,” a very stigmatizing phrase, and not something that really exists. The phrase “bipolar meltdown” could refer to a bipolar person having a manic episode or being in a depressed state.
With bipolar rage there does not necessarily need to be a trigger, it can show up without warning and is always absent of reason. It chooses chaos, it's not the individual choosing to lose control. If anything, control is something we're desperate to have and that desperation only makes our anger more chaotic.
Cardiovascular complications of PCOS. Women with unmanaged or untreated PCOS are more prone to heart and cardiovascular diseases. This is because of a wide range of coexisting conditions like insulin resistance, high cholesterol and triglyceride levels, and high blood pressure.