While antidepressants can treat the symptoms of depression, they don't always address its causes. This is why they're usually used in combination with therapy. This helps to treat more severe depression or other mental health conditions.
Antidepressants can also relieve long-term symptoms of chronic depressive disorder (dysthymia) and chronic depression, and help make them go away completely. An antidepressant can already have an effect within one or two weeks. But it may take longer for the symptoms to improve.
So do antidepressants work as a permanent cure for depression? No, they do not, and the reason for this lies in how they work. While they cause changes in brain chemistry, this effect is only temporary. When you stop taking the antidepressant, your brain chemistry will return to its previous state.
However, the rate of treatment response from baseline symptoms following first-line treatment with SSRIs is moderate, varying from 40 to 60 percent; remission rates vary from 30 to 45 percent. Up to one third of persons on drug treatment will develop recurrent symptoms of depression while on therapy.
There is no cure for depression, but many different treatments are available to manage the symptoms. The symptoms of depression vary among individuals. A treatment plan that includes medical interventions, support, and lifestyle changes can enable a person to live a normal and full life with the condition.
Introduction. The idea that depression is the result of abnormalities in brain chemicals, particularly serotonin (5-hydroxytryptamine or 5-HT), has been influential for decades, and provides an important justification for the use of antidepressants.
Antidepressants can cause changes in neurotransmitter levels and brain function; however, these changes are typically reversible once the medication is stopped.
Clinicians usually recommend that people continue taking antidepressants for about six months after they begin feeling better. Although it is tempting to stop taking the medication as soon as you feel better, abruptly stopping will greatly increase your risk of relapse.
It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
Researchers have linked low levels of serotonin with mood disorders, such as depression and anxiety.
The data available suggest that low serotonin levels do not cause depression. However, this does not mean that doctors will stop utilizing antidepressants as a treatment option. Instead, it calls for more research about why antidepressants work the way they do.
The serotonin hypothesis says that depression is caused by not enough of a chemical messenger called serotonin in the brain.
Answer From Daniel K. Hall-Flavin, M.D. Depression ranges in seriousness from mild, temporary episodes of sadness to severe, persistent depression.
Persistent depressive disorder symptoms usually come and go over a period of years. The intensity of symptoms can change over time. But symptoms usually don't disappear for more than two months at a time. Also, major depression episodes may occur before or during persistent depressive disorder.
Achieving remission after a major depressive episode is possible, even if you've experienced recurrent depression in the past. Depression recovery often depends on several factors.
Symptoms of Chemical Imbalances
Studies show that brain chemicals play a role in the development of anxiety and depression. Lower levels of neurotransmitters can cause symptoms, such as feelings of emptiness, worthlessness, sadness, or helplessness. These symptoms can lead to various mental conditions.
There's no single cause of depression. It can occur for a variety of reasons and it has many different triggers. For some people, an upsetting or stressful life event, such as bereavement, divorce, illness, redundancy and job or money worries, can be the cause. Different causes can often combine to trigger depression.
Medications and psychotherapy are effective for most people with depression. Your primary care doctor or psychiatrist can prescribe medications to relieve symptoms. However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional.
Depression is a common mental disorder. Globally, it is estimated that 5% of adults suffer from the disorder. It is characterized by persistent sadness and a lack of interest or pleasure in previously rewarding or enjoyable activities. It can also disturb sleep and appetite.
The serotonin test measures the level of serotonin in the blood. Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.
MDMA causes greater release of serotonin and norepinephrine than of dopamine. Serotonin is a neurotransmitter that plays an important role in the regulation of mood, sleep, pain, appetite, and other behaviors. The excess release of serotonin by MDMA likely causes the mood-elevating effects people experience.
Certain drugs and substances such as caffeine, alcohol, nicotine, NutraSweet, antidepressants, and some cholesterol-lowering medications deplete serotonin and other neurotransmitter levels. Hormone changes cause low levels of serotonin and neurotransmitter imbalances.
Low levels of dopamine can make you feel tired, moody, unmotivated and many other symptoms. Treatments are available for many of the medical conditions linked to low dopamine levels.