Symptoms may include: Fatigue. Pruritus (itchy skin), especially after warm baths or showers. Reddened face and burning feeling on the skin.
Cancer treatment—including chemotherapy, targeted therapy, and immunotherapy—can cause skin issues in people with leukemia. Per the American Cancer Society (ACS), the rashes can appear across multiple areas of the body (e.g., scalp, neck, upper body) and may be itchy, burning, stinging, or painful.
In very rare cases, itchy skin can be caused by a serious underlying condition such as leukaemia. According to our patient survey “Living Well with Leukaemia”, around 9% of people with leukaemia will experience itchy skin as a symptom prior to their diagnosis.
In addition, itching associated with cancer may feel the worst on the lower legs and chest and may be associated with a burning sensation.
Itching is a common symptom of skin lymphoma, T-cell lymphoma, and Hodgkin's lymphoma. Itching is less common in most types of non-Hodgkin's lymphoma. The itching might be caused by chemicals released by the immune system in reaction to the lymphoma cells.
See your doctor or a skin disease specialist (dermatologist) if the itching: Lasts more than two weeks and doesn't improve with self-care measures. Is severe and distracts you from your daily routines or prevents you from sleeping. Comes on suddenly and can't be easily explained.
The most common symptoms of leukemia—fatigue, pale skin, weight loss and night sweats—are often attributed to other less serious conditions, such as the flu.
Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.
In CLL, the leukemia cells grow out of control and crowd out normal blood cells. These cells often build up slowly over time. Many people don't have any symptoms for at least a few years. In time, the cells can spread to other parts of the body, including the lymph nodes, liver, and spleen.
Symptoms and Causes
People with iron deficiency anemia may experience itchy skin (pruritis) that can become red, bumpy and sore when scratched. Rashes associated with aplastic anemia usually appear as tiny red or purple dots under your skin (petechiae).
Both vitamin B12 and vitamin A deficiencies may also cause itchy skin, so if you are experiencing chronically itchy skin, getting your level of these vitamins tested can be helpful. This testing will help determine whether these deficiencies are at the root of your skin sensitivities and itchiness.
Common causes of itching
skin conditions – such as eczema. allergies or skin reactions. parasitic infestations – such as scabies. insect bites and stings.
What is Leukemia (Blood Cancer)? Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Leukemia is a cancer of the blood, so its impact begins in your blood cells. First, your body begins producing too many immature white blood cells. These cells are cancerous and overwhelm the other cells in your bloodstream. Over time, this can affect your red blood cells, platelets, and healthy white blood cells.
So while you may be able to see if you have genetic markers for future cancer development, there's currently no home test available that can tell you whether you have leukemia currently. Possible tests available for home use can give you an idea of your overall health and risk factors, but they can't diagnose leukemia.
"A patient may be tested for leukemia if he or she has unexplained weight loss, night sweats or fatigue, or if he or she bruises or bleeds easily," Dr. Siddon says. "Sometimes routine blood work shows an unexplained elevated number of white blood cells."
Blood tests.
By looking at a sample of your blood, your doctor can determine if you have abnormal levels of red or white blood cells or platelets — which may suggest leukemia. A blood test may also show the presence of leukemia cells, though not all types of leukemia cause the leukemia cells to circulate in the blood.
A blood test showing an abnormal white cell count may suggest the diagnosis. To confirm the diagnosis and identify the specific type of leukemia, a needle biopsy and aspiration of bone marrow from a pelvic bone will need to be done to test for leukemic cells, DNA markers, and chromosome changes in the bone marrow.
Leukemia is commonly misdiagnosed as the following conditions: Influenza. Fever. Pathological fracture.
While the exact cause of leukemia—or any cancer, for that matter—is unknown, there are several risk factors that have been identified, such as radiation exposure, previous cancer treatment and being over the age of 65.
Age: The risk of most leukemias increase with age. The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older. However, most cases of acute lymphocytic leukemia (ALL) occur in people under 20 years old.
Dry skin is a common cause of itchy skin without a rash. In most cases, dry skin is mild. It can result from environmental conditions, such as low humidity and hot or cold weather. It's also sometimes caused by activities that can decrease moisture in the skin, such as bathing in hot water.
Cytokines can irritate nerve endings in the skin, which can in turn cause persistent itching. Many individuals experience this itchiness in their hands, lower legs or feet, while others feel it throughout their entire body. Patients often report that the itching tends to worsen while they are lying in bed at night.
Dry skin: Your body loses moisture at night, which can make your skin itchy. Hormonal changes: At night, your body doesn't produce as many hormones as it does during the day and certain hormones reduce inflammation (swelling). As you have fewer hormones at night, your skin could be itchy.