Abuse of paracetamol can cause damage on your liver, while abuse of ibuprofen can cause damage to your stomach or liver. It's safer to take paracetamol if you are pregnant than ibuprofen. (In the case of the latter, you should consult your doctor first, but completely avoid it in your 3rd trimester)
Luckily, a low dose of paracetamol is perfectly safe for everyone with liver disease. That means you can take 4 to 6 tablets in one day. Non-steroidal anti-inflammatory drugs like ibuprofen and aspirin are not the best choice of painkiller for people with liver disease as they can affect the kidneys.
What painkiller does not affect the liver? Acetaminophen (paracetamol), when taken in reduced doses (maximum 2–3 grams per day), is generally considered to be the safest pain relief option for your liver.
Acetaminophen or Tylenol® is the best known medication that can damage the liver. This medication is widely available without prescription and is present in many of the cold and flu remedies as well as in prescribed pain medications.
Ibuprofen has the highest liver safety profile among NSAIDs and showed no severe liver injury in larger studies. Along with paracetamol and aspirin, it is considered one of the most common over the counter NSAIDs sold in the world. Coxibs have currently replaced several NSAIDs due to safer GI profile.
Certain NSAIDs such as diclofenac and naproxen have been associated with hepatotoxicity. Therefore, low-dose acetaminophen (2 grams or less/day on non-consecutive days) is preferred over NSAIDs in patients with chronic liver disease.
Acetaminophen remains the drug of choice for occasional use in patients with kidney disease because of bleeding complications that may occur when these patients use aspirin.
HEPATOTOXICITY RISK FACTORS
While acute liver injury can occur when used at or below the recommended daily maximum dose (4000 mg)[4], paracetamol toxicity is often the result of ingestion of paracetamol over this maximum dose.
Limit the amount of alcohol you drink. Eat a well-balanced diet every day. That's five to nine servings of fruits and vegetables, along with fiber from vegetables, nuts, seeds, and whole grains. Be sure to include protein for the enzymes that help your body detox naturally.
Non-steroidal anti-inflammatory drugs, or NSAIDs, like ibuprofen rarely affects the liver. Most users have little risk of liver damage from ibuprofen medication.
Acetaminophen. Taking acetaminophen in excess is the leading cause of drug-induced liver injury.
Unless a doctor instructs otherwise, a person should not take ibuprofen for longer than 10 days in a row.
Paracetamol overdose is one of the leading causes of acute liver failure. Adults can usually take one or two 500mg tablets every 4-6 hours, but shouldn't take more than 4g (eight 500mg tablets) in the space of 24 hours.
Do not use for more than a few days at a time unless your doctor tells you to. Do not take more than the recommended dose unless your doctor tells you to. Do not use PANADOL OSTEO to treat any other complaints unless your pharmacist or doctor tells you to.
Taking 1 or 2 extra tablets is unlikely to harm you. Do not take more than 8 tablets in 24 hours. Taking too much paracetamol can be dangerous and you may need treatment.
Untreated paracetamol poisoning may cause varying degrees of liver injury over the 2 to 4 days following ingestion, including fulminant hepatic failure.
The symptoms of acute liver failure caused by a paracetamol overdose include: A yellow colour to your eyes or skin (jaundice) Low blood sugar. Sweating.
Foods that support liver health include berries, cruciferous vegetables, beans, whole grains, nuts, and fatty fish. Coffee and green tea contain antioxidants that are helpful for liver health.
It is estimated that alcohol-related fatty liver disease develops in 90% of people who drink more than 40g of alcohol (or four units) per day. That's roughly the equivalent of two medium (175ml) glasses of 12% ABV wine, or less than two pints of regular strength (4% ABV) beer.
Vitamin D. Vitamin D is one of the essential vitamins for the liver, which helps to prevent metabolic liver disease and inflammatory disease. As per a study conducted in 2009, 92% of the total 118 people who are suffering from chronic liver disease have vitamin D deficiency.
Stay Away From Fatty Foods
Eat too many foods that are high in saturated fat and it can make it harder for your liver to do its job. Over time it may lead to inflammation, which in turn could cause scarring of the liver that's known as cirrhosis.