Blood tests can help your doctors detect the presence of some of the telltale signs of non-Hodgkin lymphoma. These may include anemia, or low levels of red blood cells, which are needed to carry oxygen to the body's organs and tissues. A common symptom of anemia is fatigue.
Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.
The normal range of white blood cells per microliter is: 5,000 to 10,000 for men. 4,500 to 11,000 for women. 5,000 to 10,000 for children.
Complete blood count (CBC).
This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
LDH Test. Lactate dehydrogenase (LDH) levels are often higher in people with lymphoma. Doctors may order a blood test to check for the LDH level.
With lymphoma, the lymph nodes often grow slowly and may be there for months or years before they're noticed. But sometimes they grow very quickly. Usually, the swollen nodes don't hurt. But some people say their lumps ache or are painful.
Itching caused by lymphoma can affect: areas of skin near lymph nodes that are affected by lymphoma. patches of skin lymphoma. your lower legs.
Getting a Second Opinion. NHL is a difficult disease to diagnose, therefore you may want to get a second opinion by an experienced hematopathologist before you begin treatment. Some types of NHL can be confused with one other.
Low-Grade Lymphoma
These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
NHL usually starts in the lymph nodes. It is quite common to find it in the neck, liver or spleen. But it can also be found in other body organs, such as the stomach, small bowel, bones, brain, testicles or skin. Although very uncommon, it can also affect the eye.
Lymphomas are cancers that start in white blood cells called lymphocytes.
The only way to be absolutely sure of a diagnosis of lymphoma (or any other cancer) is for a doctor to conduct medical tests including performing an excisional biopsy to remove an entire lymph node or an incisional biopsy to remove a portion of the diseased tissue.
For stage I NHL, the 5-year relative survival rate is more than 86%. For stage II the 5-year relative survival rate is 78%, and for stage III it is more than 72%. For stage IV NHL, the 5-year relative survival rate is almost 64%.
feeling uncomfortably full or feeling sick caused by a swelling in your stomach area. itching either widespread or in one place. bone pain if the lymphoma affects the bone marrow inside your bones. skin rashes or lumps.
Many types of CTCL start as flat red patches on the skin, which can sometimes be itchy. With darker skin, the patches may appear lighter or darker than the surrounding skin. In the early stages, the skin patches can look like other common conditions such as eczema or psoriasis.
Cancer-related fatigue is exhaustion that's at a much higher level than would usually be expected – you might feel tired very quickly after doing quite little. It can be physical, emotional or mental exhaustion.
Advanced tests can determine if lymphoma cells are present and what types of cells are involved. Blood tests. Blood tests to count the number of cells in a sample of your blood can give your doctor clues about your diagnosis. Removing a sample of bone marrow for testing.
Misdiagnosis of Lymphoma
Lymphoma can be misdiagnosed or fail to be diagnosed if a physician mistakes symptoms for another disease and fails to do a biopsy or blood test.
Kikuchi-Fujimoto disease.
Ultrasound is used to detect lymphoma and assist in diagnosing the disease. Ultrasound is just one of many imaging tests used for diagnosing lymphoma, including: Computed tomography (CT) scans. Positron emission tomography (PET) scans.
Diffuse large B cell lymphoma
This fast-growing lymphoma accounts for about one third of NHL cases. For this lymphoma, it is typical for lymph nodes to double in size every month, and patients often present within a few months of having noted an enlarged lymph node.
Blood tests may include a complete blood count (CBC) and an analysis of the different types of white blood cells, in addition to the erythrocyte sedimentation rate (ESR or "sed rate") and liver and kidney function tests. Blood tests alone cannot detect Hodgkin lymphoma. Computed tomography (CT or CAT) scan.