Synthetic vitamin D blocks the synthesis of collagen, which is shown here as light blue fibers. Another Role for Vitamin D? Vitamin D is beneficial in many ways. It helps build strong bones, heals skin, aids in calcium absorption, and boosts the immune system.
1,25-Dihydroxyvitamin D3 increases collagen production in dermal fibroblasts.
25-Hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 also inhibited collagen synthesis by cultures of growth cartilage but only at higher metabolite concentrations.
Vitamin C (VitC) plays a critical role in the maintenance of a normal mature collagen network in humans (anti-scurvy properties) by preventing the auto-inactivation of lysyl and prolyl hyroxylase, two key enzymes in collagen biosynthesis.
Besides time, three main things will lower your collagen levels: sunlight, smoking, and sugar. Too much exposure to ultraviolet light makes its fibers unravel. This can lead to sun damage, such as wrinkles.
Here's one possibility as to why: Vitamin D is known to reduce inflammation and inflammation is one of the causes of skin conditions, such as acne, eczema, psoriasis, rashes and more. Other research connects vitamin D as being important for skin cell growth, skin protection and supporting skin immunity.
Vitamin D3 also stimulates collagen production which improves elasticity and lessens fine lines and wrinkles. It reduces pigment discoloration and the appearance of dark spots and redness.
As far as your skin is concerned, vitamin D showcases great anti-inflammatory properties that can help treat skin conditions like dryness, acne, psoriasis, eczema, and vitiligo. Many cosmetic brands and even dermatologists use this vitamin in night creams and moisturisers to help improve your skin.
Vitamin C (Vit C) benefits to human skin physiology notably by stimulating the biosynthesis of collagen. The main cutaneous collagens are types I and III, which are less synthesized with aging. Vit C is one of the main promotors of collagen formation but it poorly bypasses the epidermis stratum corneum barrier.
Vitamin D may promote healthy aging.
The authors studied epigenetic patterns in 1,600 participants and found that people with low Vitamin D in their blood were “biologically older” than people who had adequate levels — also described as age acceleration.
Topical application of vitamin D3 has been shown to render protection against damage caused to the skin by UV light. Vitamin D reduces cell death, promotes cell survival and reduces redness due to photodamage of skin caused by UV radiation, to some extent.
Due to vitamin D's antioxidant properties, it may help stimulate the growth of collagen and elastin. Healthy vitamin D levels do have the potential to prevent premature ageing, but too much sun can accelerate skin ageing.
Research has also shown that vitamin D is effective in preventing premature aging by protecting the skin from ultraviolet light, one of the most common causes of wrinkles and lines.
Although there is no scientific evidence that vitamin D can have a direct effect on the under-eye area, it is believed that puffy eyes and dark circles prevail in people deficient in vitamin D, particularly females aged 40+.
The main consequence of vitamin D toxicity is a buildup of calcium in your blood (hypercalcemia), which can cause nausea and vomiting, weakness, and frequent urination. Vitamin D toxicity might progress to bone pain and kidney problems, such as the formation of calcium stones.
tl;dr. There's no set time of day that's best to take vitamin D supplements. Some people say taking vitamin D supplements at night is an insomnia risk. There's no research to confirm this, but you might want to take your supplement earlier in the day if you think it's screwing with your sleep.
Eat a healthy diet high in nutrients including vitamins A11 and C. Follow a daily skin care routine that includes sunscreen and topical retinol. Avoid smoking, as research shows that tobacco smoke reduces the production of collagen and elastin.
Environmentally Induced Loss of Collagen
The #1 cause of premature aging in the skin is caused by exposure to the sun. The sun has the ability to break down collagen in the skin, resulting in fine lines and wrinkles.
#1 Vitamin C
Among the nutrients needed for collagen synthesis, vitamin C may be considered one of the most vital. This is due to its role in converting a specific amino acid, proline, into a collagen-building compound.
Free radicals damage collagen — “they are our skin's enemy,” says Dr. Zeichner. Environmental factors (like UV rays or pollution), bad lifestyle habits (smoking), and a poor diet (for example, one high in sugar) all create free radical formation, which speeds collagen breakdown.
“External insults” that cause collagen breakdown occur when the skin is exposed to the sun's ultraviolet rays, environmental pollutants, or certain skin-disruptive microorganisms.