Mebendazole is the safest and well-tolerated antiparasitic medicine, well-effective when taken as prescribed dosages.
Taking an extra dose of mebendazole is unlikely to harm you. However, you may get side effects such as: stomach cramps. feeling or being sick (nausea or vomiting)
Stomach/abdominal pain, vomiting, diarrhea, headache, dizziness, or drowsiness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
Mebendazole kills worms that cause gut infections such as threadworm (sometimes known as pinworm) and other less common worm infections (whipworm, roundworm and hookworm). It works by stopping the worms using sugar (glucose). Without glucose, the cells of the worms lose their energy supply and quickly die.
Peak plasma concentrations of mebendazole occur approximately 0.5–7 hours after oral administration of the drug and exhibit wide interpatient variation.
Mebendazole is usually well tolerated and the liver injury reported with its use has been mild and self-limited in course. Patients with hypersensitivity and acute liver injury attributed to mebendazole should avoid repeat exposure.
Mebendazole works by preventing the threadworms absorbing sugar, which means they should die within a few days. This medication is 90-100% effective at killing the threadworms, but it doesn't kill the eggs. This is why the hygiene measures outlined below should also be followed for 6 weeks.
Side effects of deworming are rare. In some rare cases, children can experience dizziness, headache, nausea, and vomiting after deworming. This is just the effect of the worm passing through the body. Consult a doctor immediately if these symptoms do not go away even after a day.
Note: Deworming drugs can cause some side effects such as nausea, dizziness, headache, digestive disorders, abdominal pain, transient diarrhea. However, you do not need to worry too much, because these symptoms are usually mild and go away on their own.
After being dewormed, dogs and puppies may suffer some mild side effects, including: lack of appetite. gastrointestinal upset. vomiting.
Mebendazole is not suitable for some people. To make sure it's safe for you, tell a pharmacist or doctor if you: have ever had an allergic reaction to mebendazole or any other medicine. are pregnant or breastfeeding.
Mebendazole (Emverm) is used to treat pinworm, whipworm, roundworm, and hookworm infections. Mebendazole is in a class of medications called anthelmintics. It works by killing the worms.
Other drugs are used to treat worm infections outside the digestive tract, as mebendazole is poorly absorbed into the bloodstream. Mebendazole is used alone in those with mild to moderate infestations.
You'll likely need to give your doctor a stool sample for a few months to make sure all the worms are gone.
The Deworming Process after a Few Days
Some intestinal worms, like hookworms and whipworms, are so small that you won't see any worms in your dog's stool at all. You may be surprised to still see live worms in your dog's feces after deworming them, but this is normal.
Any worms in your gut will eventually pass out in your poo. You may not notice this. To avoid becoming infected again or infecting others, it's very important during the weeks after starting treatment to wash your hands: after going to the toilet.
Gut microbiota diversity increased after Enterobius infection, and it peaked after administration of mebendazole. At the phylum level, pinworm infection and mebendazole deworming were associated with a decreased relative abundance of Fusobacteria and an increased proportion of Actinobacteria.
This medicine may cause serious skin reactions when taken together with metronidazole. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.
If you are self-treating for pinworms, take the medication once only. Do not repeat the dose without talking with your doctor first. Depending on the type of worm infection you have, your doctor may direct you to take the medication only once or for several days.
Mebendazole is best taken with meals, especially fatty ones (eg, meals that include whole milk or ice cream). This helps to clear up the infection by helping your body absorb the medicine better. However, if you are on a low-fat diet, check with your doctor.
The apparent elimination half-life after an oral dose ranges from 3 to 6 hours in most patients. Less than 2% of orally administered mebendazole is excreted in urine and the remainder in the feces as unchanged drug or its metabolites.
Deworming programmes only rely on one drug
Deworming programmes are currently relying on just two drugs namely, albendazole or mebendazole. Both these drugs work in the same way. Therefore if the worms develop a resistance to one it's likely they'll also be resistant to the other.