Drinking plenty of water every day is essential for all bodily functions, including the regulation of histamine levels. Water does aid in the removal of histamines from the body as more that 95% of excess histamines are removed from the body through the urine.
Histamine levels are another potent downstream target. Allergic symptoms exacerbate during nighttime and plasma histamine levels exhibit nocturnal peaks.
Within the brain, histamine is responsible for regulating the cycle of sleeping and waking. Histamine is most active while we're awake, and is more active during the phase of the sleep cycle that most closely resembles wakefulness than it is during deeper sleep.
Your body releases higher levels of histamine naturally at night as well as after meals so taking activated charcoal at night (about two hours after an early dinner) sweeps up excess histamine and can alleviate some, if not all of the symptoms associated with high histamine at night.
These include: Flushing, difficulty regulating body temperature, sudden excessive sweating. Hives, rashes, swelling, itchy skin, eczema. Racing heart, palpitations, arrhythmia.
For these people, histamine builds up in the body and is not broken down correctly. This can trigger an immune system response resulting in symptoms such as diarrhea, shortness of breath, headaches, or skin irritation.
Natural antihistamines may help you control your seasonal allergies. Common ones are stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics. Some alternative practices—such as acupuncture, nasal irrigation, and exercise—may also help you manage symptoms.
If you have a food allergy, histamines are in on that response process, too. When you accidentally eat or drink something you shouldn't, they'll work in your gut to trigger your allergic reaction. Some foods are also naturally high in histamines. These include aged and fermented foods and alcohol (especially red wine).
Histamine intolerance is more common in people with underlying digestive issues. Conditions such as inflammatory bowel disease, celiac disease, IBS, and SIBO increase the risk of histamine intolerance. There is minimal information on the actual incidence of HIT. Its correlation with other health issues is emerging.
Histamine intolerance can manifest a wide range of symptoms, ranging from inconvenient to completely debilitating. Autoimmune Disease and allergic disorders like histamine intolerance and MCAS share key features, including that both are the result of a hypersensitive immune system gone wild.
Vitamin B6 and Vitamin C, in particular, have been shown to reduce symptoms of seasickness and histamine intolerance.
Vitamin C is a natural antihistamine, which means it can lower histamine levels and mitigate allergic reactions and symptoms. Consume plenty of Vitamin C rich foods, like tropical fruits, citrus fruits, broccoli and cauliflower, and berries.
An antihistamine is a prescription or over-the-counter medication that blocks some of what histamine does. “Anti” means against, so antihistamines are medicines that work against or block histamine.
While there is no solid evidence to prove the connection between histamine and mental disorders, symptoms like hyperactivity, obsessive-compulsive behavior, panic, anxiety, and depression are often observed among those who suffer from histamine imbalance.
As part of this stress response, the sympathetic nervous system can further activate the immune system, leading to mast cell degranulation and the release of even more histamine into the bloodstream. Histamine and stress are related in this way, with the outcome being that stress increases histamine release.
Treating Histamine Intolerance: Diet, Probiotics, & Supplements. A low histamine diet, coupled with a DAO enzyme and gut health support is the best option available to help you reduce your histamine burden and resolve histamine intolerance symptoms.
Tri-Magnesium 90 Veg Caps. A common deficiency seen in histamine intolerance is magnesium. Magnesium is involved in over 300 reactions in the body, so depletion of this nutrient can cause big interruptions in standard biological processes.
Vitamin C: lowers the histamine level in the blood. Vitamin B6: is an important co-factor of the enzyme diamine oxidase and its activity. Calcium: reduces the development of wheals and flushing of the skin. Zinc: has anti-allergic and anti-inflammatory properties and constrains histamine release.
Claritin and Zyrtec are effective and safe for most people with minor allergies.
Histamine release is primarily caused by morphine, followed by hydromorphone, and is least likely to occur with fentanyl. Other commonly used sedatives, such as propofol and benzodiazepines, have a direct vasodilatory effect.
What foods are highest in histamine? High histamine foods include fermented foods, alcohol, aged cheeses, eggplant, avocado, citrus foods, dried fruit, legumes, and processed meats.